1-Piperazinecarboxylicacid, 4-(diphenylmethyl)-, ethyl ester

Base Information

• Chemical Name: 1-Piperazinecarboxylicacid, 4-(diphenylmethyl)-, ethyl ester
• CAS No.: 102552-76-1
• Molecular Formula: C20H24 N2 O2
• Molecular Weight: 324.423
• Mol file: 102552-76-1.mol

Synonyms:

Chemical Property of 1-Piperazinecarboxylicacid, 4-(diphenylmethyl)-, ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Piperazinecarboxylicacid, 4-(diphenylmethyl)-, ethyl ester

There total 1 articles about 1-Piperazinecarboxylicacid, 4-(diphenylmethyl)-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-ethoxycarbonylpiperazine (120-43-4) + diphenylchloromethane (90-99-3) → 1-benzhydryl-4-(ethoxycarbonyl)piperazine (102552-76-1)

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 ℃; for 24h;

DOI:10.1016/j.bmc.2007.08.034

Reference yield: 88.0%

1-benzhydryl-4-(ethoxycarbonyl)piperazine (102552-76-1) → diphenylmethylpiperazine (841-77-0)

Guidance literature:

With potassium hydroxide; In ethanol; for 6h; Heating;

Reference yield:

1-benzhydryl-4-(ethoxycarbonyl)piperazine (102552-76-1) → oxatomide (60607-34-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / KOH / ethanol / 6 h / Heating

2: 64 percent / triethylamine, KI / toluene / 20 h / Heating

With potassium hydroxide; triethylamine; potassium iodide; In ethanol; toluene;

upstream raw materials:

4-ethoxycarbonylpiperazine

diphenylchloromethane

Downstream raw materials:

diphenylmethylpiperazine

N-benzhydryl-N'-methylpiperazine

2-[4-(diphenylmethyl)-1-piperazinyl]-acetic acid

4-(4-Benzhydryl-piperazin-1-yl)-butyric acid ethyl ester

Refernces