(R)-pindolol

Base Information

Chemical Name:(R)-pindolol
CAS No.:68374-35-6
Molecular Formula:C14H20 N2 O2
Molecular Weight:248.325
Hs Code.:
DSSTox Substance ID:DTXSID40218506
Nikkaji Number:J221.535G
Wikidata:Q27121120
Pharos Ligand ID:RM3D979CPGH7
Metabolomics Workbench ID:56923
ChEMBL ID:CHEMBL1530633
Mol file:68374-35-6.mol

Synonyms:(R)-pindolol;(R)-(+)-pindolol;(+)-pindolol;CHEBI:48280;68374-35-6;(2R)-1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol;(2R)-1-(1H-indol-4-yloxy)-3-[(propan-2-yl)amino]propan-2-ol;(2R)-1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-2-propanol;2-Propanol, 1-(1H-indol-4-yloxy)-3-((1-methylethyl)amino)-, (R)-;CAS-13523-86-9;Tocris-0994;Lopac-P-152;Lopac-P-152-Batch2;Lopac-P-0778;SCHEMBL1157556;CHEMBL1530633;DTXSID40218506;PDSP1_001585;PDSP2_001569;NCGC00015786-01;NCGC00015786-02;NCGC00015786-03;NCGC00015786-04;NCGC00015786-05;NCGC00015786-12;NCGC00016700-01;NCGC00024925-01;Q27121120;(R)-1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol

Suppliers and Price of (R)-pindolol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-pindolol

Chemical Property:

Vapor Pressure:3.77E-09mmHg at 25°C
Boiling Point:457.1°C at 760 mmHg
PKA:13.94±0.20(Predicted)
Flash Point:230.3°C
PSA：57.28000
Density:1.152g/cm³
LogP:2.29650
XLogP3:1.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:248.152477885
Heavy Atom Count:18
Complexity:248

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)NCC(COC1=CC=CC2=C1C=CN2)O
Isomeric SMILES:CC(C)NC[C@H](COC1=CC=CC2=C1C=CN2)O

Technology Process of (R)-pindolol

There total 2 articles about (R)-pindolol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 67-64-1
acetone

: 160319-71-1
(S)-4-(2-hydroxy-3-nitropropoxy)indole

: 68374-35-6
(+)-Pindolol

: 26328-11-0
(S)-pindolol

Guidance literature:: With platinum(IV) oxide; hydrogen; In methanol; at 50 ℃; for 16h;
DOI:10.1016/S0040-4020(01)89540-5

Reference yield:

: 13523-86-9
1-(1H-indol-4-yloxy)-3-(isopropylamino)-2-propanol

: 68374-35-6
(+)-Pindolol

: 26328-11-0
(S)-pindolol

Guidance literature:: resolving agent: trans-cellulose tris(4-phenylazophenylcarbamate) ( CPAPC ) adsorbed on silica gel; optical resolution degree examined by HPLC on cis/trans-CPAPC;
DOI:10.1246/cl.1986.983