2-acetylbenzoic acid methyl ester dimethylketal

Base Information

• Chemical Name: 2-acetylbenzoic acid methyl ester dimethylketal
• CAS No.: 209742-36-9
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.257
• Mol file: 209742-36-9.mol

Synonyms:

Chemical Property of 2-acetylbenzoic acid methyl ester dimethylketal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-acetylbenzoic acid methyl ester dimethylketal

There total 2 articles about 2-acetylbenzoic acid methyl ester dimethylketal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

methyl 2-acetylbenzoate (1077-79-8) + trimethyl orthoformate (149-73-5) → 2-acetylbenzoic acid methyl ester dimethylketal (209742-36-9)

Guidance literature:

With Montmorillonite clay K-10; for 16h;

DOI:10.1055/s-1998-1734

Reference yield:

potassium 2-acetylbenzoate (16727-00-7) → 2-acetylbenzoic acid methyl ester dimethylketal (209742-36-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / dimethylsulfoxide

2: 78 percent / montmorillonite clay K-10 / 16 h

With Montmorillonite clay K-10; In dimethyl sulfoxide;

DOI:10.1055/s-1998-1734

Reference yield: 75.0%

phenethylamine (64-04-0) + 2-acetylbenzoic acid methyl ester dimethylketal (209742-36-9) → 3-methylene-2-phenethyl-2,3-dihydroisoindol-1-one (209742-39-2)

Guidance literature:

With scandium tris(trifluoromethanesulfonate);

DOI:10.1055/s-1998-1734

upstream raw materials:

methyl 2-acetylbenzoate

trimethyl orthoformate

potassium 2-acetylbenzoate

Downstream raw materials:

[2-(1,1-Dimethoxy-ethyl)-phenyl]-methanol

2-(3,4-dimethoxyphenethyl)-3-methyleneisoindolin-1-one

3-methylene-2-phenethyl-2,3-dihydroisoindol-1-one

1-(1-hydroxyethyl)-2-hydroxymethylbenzene