5-Iodo-2-methoxyaniline

Base Information

Chemical Name:5-Iodo-2-methoxyaniline
CAS No.:77770-09-3
Molecular Formula:C7H8INO
Molecular Weight:249.051
Hs Code.:2922299090
European Community (EC) Number:678-942-2
DSSTox Substance ID:DTXSID30512626
Nikkaji Number:J2.246.607K
Wikidata:Q72483756
Mol file:77770-09-3.mol

Synonyms:2-Amino-4-iodoanisole;5-iodo-2-methoxyaniline;77770-09-3;2-METHOXY-5-IODOANILINE;MFCD03095407;5-Iodo-o-anisidine;Benzenamine, 5-iodo-2-methoxy-;5-iodo-2-methoxybenzenamine;5-iodo-2-methoxy-phenylamine;SCHEMBL111536;DTXSID30512626;KCAGMESWEMVFON-UHFFFAOYSA-N;CDA77009;AKOS005201873;CS-W014107;DS-12918;SY022937;FT-0641656;A19887;EN300-1262432

Suppliers and Price of 5-Iodo-2-methoxyaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
5-Iodo-2-methoxyaniline 98%
5 g
$ 141.00

Labseeker
5-Iodo-2-methoxyaniline 95
50g
$ 850.00

Chemenu
5-Iodo-2-methoxyaniline 95+%
5g
$ 111.00

Chemenu
5-Iodo-2-methoxyaniline 95+%
10g
$ 186.00

American Custom Chemicals Corporation
5-IODO-2-METHOXYANILINE 95.00%
5G
$ 965.35

American Custom Chemicals Corporation
5-IODO-2-METHOXYANILINE 95.00%
1G
$ 654.89

Alichem
2-Amino-4-iodoanisole
500mg
$ 806.85

Alichem
2-Amino-4-iodoanisole
1g
$ 1460.20

Alichem
2-Amino-4-iodoanisole
250mg
$ 484.80

Alfa Aesar
5-Iodo-2-methoxyaniline, 97%
1g
$ 57.00

Total 34 raw suppliers

Chemical Property of 5-Iodo-2-methoxyaniline

Chemical Property:

Vapor Pressure:0.000884mmHg at 25°C
Melting Point:85-87°C
Refractive Index:1.647
Boiling Point:304.3 °C at 760 mmHg
PKA:3.58±0.10(Predicted)
Flash Point:137.8 °C
PSA：35.25000
Density:1.807 g/cm³
LogP:2.46320
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive.:Light Sensitive
Water Solubility.:Sparingly soluble in water 0.87 g/L @ 25°C.
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:248.96506
Heavy Atom Count:10
Complexity:110

Purity/Quality:

97% ^*data from raw suppliers

5-Iodo-2-methoxyaniline 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)I)N
Uses 5-Iodo-2-methoxyaniline is used as a pharmaceutical intermediate.

Technology Process of 5-Iodo-2-methoxyaniline

There total 5 articles about 5-Iodo-2-methoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 696-62-8
para-iodoanisole

: 77770-09-3
3-amino-4-methyloxyphenyliodide

Guidance literature:: para-iodoanisole; With pyridine; trifluorormethanesulfonic acid; tetrabutylammonium tetrafluoroborate; In acetonitrile; at 25 ℃; Electrochemical reaction;

With piperidine; In acetonitrile; at 80 ℃; for 12h; Electrochemical reaction;
DOI:10.1021/ja402083e

Reference yield: 66.0%

: 52692-09-8
4-iodo-2-nitroanisole

: 77770-09-3
3-amino-4-methyloxyphenyliodide

Guidance literature:: With tin(II) chloride dihdyrate; In ethanol; ethyl acetate; at 70 ℃; for 0.5h; Inert atmosphere;
DOI:10.1055/s-0031-1290899

Reference yield:

: 91-23-6
2-Nitroanisole

: 77770-09-3
3-amino-4-methyloxyphenyliodide

Guidance literature:: Multi-step reaction with 2 steps

1: nitric acid; iodine

2: tin; concentrated hydrochloric acid

With hydrogenchloride; tin; iodine; nitric acid;