Butanoic acid, 2-(acetylamino)-,(2S)-

Base Information

• Chemical Name: Butanoic acid, 2-(acetylamino)-,(2S)-
• CAS No.: 19146-51-1
• Molecular Formula: C6H11 N O3
• Molecular Weight: 145.158
• Mol file: 19146-51-1.mol

Synonyms:Butanoic acid, 2-(acetylamino)-,(S)-; Butyric acid, 2-acetamido-, (S)-(-)- (8CI); (S)-(-)-a-Acetamidobutyric acid; N-Acetyl-L-a-aminobutyric acid

Chemical Property of Butanoic acid, 2-(acetylamino)-,(2S)-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Butanoic acid, 2-(acetylamino)-,(2S)-

There total 6 articles about Butanoic acid, 2-(acetylamino)-,(2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(Z)-α-N-acetylamino-2-butenoic acid (65499-61-8) → (S)-N-Acetylaminobutyric acid (19146-51-1,7682-14-6) + (R)-2-acetylamino-butyric acid (34271-27-7,7682-14-6)

Guidance literature:

With hydrogen; (1S,2R,3R,4R)-(-)-2,3-bis(diphenylphosphane)bicyclo[2.2.1]hept-5-ene; chloro(1,5-cyclooctadiene)rhodium(I) dimer; In methanol; for 14h; under 825.07 Torr; Product distribution; Ambient temperature; e.e. is studied in the presence of (+)-Prophos, (-)-CpMn(CO)2-diop too;

DOI:10.1016/S0022-328X(00)99521-4

Reference yield:

2-(N-Acetylamino-)-buttersaeureethylester (62973-41-5) → (S)-N-Acetylaminobutyric acid (19146-51-1,7682-14-6) + D-2-acetylamino butanoic acid ethyl ester (105500-33-2)

Guidance literature:

In ethanol; water; at 35 ℃; for 48h; Yield given;

DOI:10.1016/S0040-4020(01)90011-0

Reference yield:

2-(N-Acetylamino-)-buttersaeureethylester (62973-41-5) → (S)-N-Acetylaminobutyric acid (19146-51-1,7682-14-6) + (R)-2-acetylamino-butyric acid (34271-27-7,7682-14-6) + D-2-acetylamino butanoic acid ethyl ester (105500-33-2)

Guidance literature:

at 35 ℃; for 48h; Yield given. Yields of byproduct given; in the present of Saccharomyces cerevisiae Hansen;

DOI:10.1016/S0040-4039(00)94256-4

upstream raw materials:

L-2-aminobutyric acid

acetic anhydride

N-(1-Ethyl-2-propinyl)acetamid

(S)-N-(1-phenylpropyl)acetamide

Downstream raw materials:

N-Acetyl-L-aspartic acid

Refernces

• 1、 Terfort. "Synthesis and application of (3R,4R)-3,4-bis(diphenylphosphino)tetrahydrofuran as ligand for asymmetric hydrogenation of acrylic acids". . p. 951 - 953. Retrieved 2007/10/02.
• 2、 Glaenzer, B.I.,Faber, K.,Griengl, H.. "ENANTIOSELECTIVE HYDROLYSIS BY BAKER'S YEAST". . p. 4293 - 4294. Retrieved 2007/10/02.