Acetamide, N-[(1S)-1-phenylpropyl]-

Base Information

• Chemical Name: Acetamide, N-[(1S)-1-phenylpropyl]-
• CAS No.: 20306-86-9
• Molecular Formula: C11H15NO
• Molecular Weight: 177.246
• Mol file: 20306-86-9.mol

Synonyms:

Chemical Property of Acetamide, N-[(1S)-1-phenylpropyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetamide, N-[(1S)-1-phenylpropyl]-

There total 72 articles about Acetamide, N-[(1S)-1-phenylpropyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-acetyl-1-phenylpropenamine (2890-85-9) → (R)-N-(1-phenylpropyl)acetamide (2698-79-5,20306-86-9,57680-92-9)

Guidance literature:

With (S,S)-ethane-1,2-bis(4-phosphacycloheptabinaphthalene); hydrogen; [rhodium(I)(norborna-2,5-diene)2]SbF₆; In methanol; at 20 ℃; for 24h; under 2068.59 Torr;

DOI:10.1016/S0040-4039(02)00877-8

Reference yield: 95.0%

1-Phenyl-1-propanol (93-54-9) + acetonitrile (75-05-8,26809-02-9) → N-(1-phenylpropyl)acetamide (20306-86-9,57680-92-9,2698-79-5)

Guidance literature:

With HClO4-functionalized silica-coated magnetic nanoparticles [γ-Fe2O3@SiO2-HClO4]; at 20 ℃; for 4h; Neat (no solvent);

DOI:10.1016/j.apcata.2010.06.014

Reference yield: 90.0%

1-phenylpropylamine (2941-20-0) + ethyl acetate (141-78-6) → (R)-N-(1-phenylpropyl)acetamide (2698-79-5,20306-86-9,57680-92-9)

Guidance literature:

With 4 A molecular sieve; Novozym-435; aluminum oxyhydroxide; palladium; In toluene; at 70 ℃; for 72h;

DOI:10.1021/ol070130d

upstream raw materials:

vinyl acetate

1-phenylpropylamine

triethylamine-1-(2-naphthylethyl)borane

cyclopropylbenzene

Downstream raw materials:

(S)-N-Acetylaminobutyric acid

1-phenylpropylamine