[1]Benzothieno[2,3-c]quinoline

Base Information

Chemical Name:[1]Benzothieno[2,3-c]quinoline
CAS No.:57289-92-6
Molecular Formula:C₁₅H₉NS
Molecular Weight:235.309
Hs Code.:
DSSTox Substance ID:DTXSID001306126
Nikkaji Number:J2.620.443G

Synonyms:[1]Benzothieno[2,3-c]quinoline;benzothieno[2,3-c]quinoline;DTXSID001306126;57289-92-6

Suppliers and Price of [1]Benzothieno[2,3-c]quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of [1]Benzothieno[2,3-c]quinoline

Chemical Property:

XLogP3:4.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:235.04557046
Heavy Atom Count:17
Complexity:293

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C3=C(C=N2)SC4=CC=CC=C43

Technology Process of [1]Benzothieno[2,3-c]quinoline

There total 4 articles about [1]Benzothieno[2,3-c]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 37942-07-7
3,5-di-tert-butyl-2-hydroxybenzaldehyde

: 873056-69-0
2-(benzo[b]thiophen-3-yl)aniline

: 2-(benzo[4,5]thieno[2,3-c]quinolin-6-yl)-4,6-di-tert-butylphenol

: 57289-92-6
<1>benzothienothieno<2,3-c>quinoline

Guidance literature:: 3,5-di-tert-butyl-2-hydroxybenzaldehyde; 2-(benzo[b]thiophen-3-yl)aniline; In toluene; at 20 ℃; for 0.166667h;

With trifluoroacetic acid; In toluene; at 100 ℃; for 16h;
DOI:10.1002/chem.201604421

Reference yield: 30.0%

: 10135-00-9
3-bromobenzo[b]thiophene-2-carbaldehyde

: 191171-55-8
2-anilineboronic acid pinacol ester

: 243-68-5
benzo[4,5]thieno[3,2-b]quinoline

: 57289-92-6
<1>benzothienothieno<2,3-c>quinoline

Guidance literature:: With 2-(cyclohexylphosphane)biphenyl; barium hydroxide octahydrate; palladium diacetate; In 1,4-dioxane; at 100 ℃; for 5h;
DOI:10.1016/j.jphotochem.2014.08.001

Reference yield:

: 615-36-1
2-bromoaniline

: 2-(benzo[4,5]thieno[2,3-c]quinolin-6-yl)-4,6-di-tert-butylphenol

: 57289-92-6
<1>benzothienothieno<2,3-c>quinoline

Guidance literature:: Multi-step reaction with 2 steps

1.1: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri tert-butylphosphoniumtetrafluoroborate; potassium carbonate / tetrahydrofuran / 16 h / 80 °C / Inert atmosphere; Sealed tube

2.1: toluene / 0.17 h / 20 °C

2.2: air / 16 h / 100 °C

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; potassium carbonate; tri tert-butylphosphoniumtetrafluoroborate; In tetrahydrofuran; toluene; 1.1: |Suzuki-Miyaura Coupling / 2.1: |Pictet-Spengler Synthesis / 2.2: |Pictet-Spengler Synthesis;
DOI:10.1002/chem.201604421