Technology Process of 1-Benzyl-5S-t-butyldiphenylsiloxy-3,4-dehydro-2-piperidon
There total 6 articles about 1-Benzyl-5S-t-butyldiphenylsiloxy-3,4-dehydro-2-piperidon which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: KOH / dimethylsulfoxide
2: H2 / Pd/C
3: imidazole / dimethylformamide / Heating
4: 1) LDA / 1) THF, hexane, -78 deg C, 30 min, 2) THF, - 78 deg C, 2 h
5: pyridine, 30percent H2O2, H2O / CH2Cl2 / 1) 0 deg C, 30 min, 2) r.t., 2 h
With
pyridine; 1H-imidazole; potassium hydroxide; water; hydrogen; dihydrogen peroxide; lithium diisopropyl amide;
palladium on activated charcoal;
In
dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1002/ardp.19913240503
- Guidance literature:
-
Multi-step reaction with 4 steps
1: H2 / Pd/C
2: imidazole / dimethylformamide / Heating
3: 1) LDA / 1) THF, hexane, -78 deg C, 30 min, 2) THF, - 78 deg C, 2 h
4: pyridine, 30percent H2O2, H2O / CH2Cl2 / 1) 0 deg C, 30 min, 2) r.t., 2 h
With
pyridine; 1H-imidazole; water; hydrogen; dihydrogen peroxide; lithium diisopropyl amide;
palladium on activated charcoal;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/ardp.19913240503
- Guidance literature:
-
With
pyridine; water; dihydrogen peroxide;
In
dichloromethane;
1) 0 deg C, 30 min, 2) r.t., 2 h;
DOI:10.1002/ardp.19913240503