1-(5-BROMO-1-BENZOTHIEN-3-YL)ETHANONE

Base Information

Chemical Name:1-(5-BROMO-1-BENZOTHIEN-3-YL)ETHANONE
CAS No.:1423-63-8
Molecular Formula:C₁₀H₇BrOS
Molecular Weight:255.135
Hs Code.:29349990
Mol file:1423-63-8.mol

Synonyms:Ketone,5-bromobenzo[b]thien-3-yl methyl (7CI,8CI);3-Acetyl-5-bromobenzo[b]thiophene;

Suppliers and Price of 1-(5-BROMO-1-BENZOTHIEN-3-YL)ETHANONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
3-Acetyl-5-bromobenzo[b]thiophene
5 g
$ 448.00

SynQuest Laboratories
3-Acetyl-5-bromobenzo[b]thiophene
1 g
$ 148.00

J&W Pharmlab
1-(5-Bromo-benzo[b]thiophen-3-yl)-ethanone 96%
500mg
$ 108.00

Frontier Specialty Chemicals
1-(5-Bromo-1-benzothien-3-yl)ethanone 97%
1g
$ 90.00

Crysdot
1-(5-Bromobenzo[b]thiophen-3-yl)ethanone 95+%
10g
$ 449.00

Chemenu
1-(5-Bromo-1-benzothiophen-3-yl)ethan-1-one 95%+
10g
$ 866.00

American Custom Chemicals Corporation
1-(5-BROMO-1-BENZOTHIEN-3-YL)ETHANONE 95.00%
5G
$ 1158.23

American Custom Chemicals Corporation
1-(5-BROMO-1-BENZOTHIEN-3-YL)ETHANONE 95.00%
1G
$ 711.39

Total 16 raw suppliers

Chemical Property of 1-(5-BROMO-1-BENZOTHIEN-3-YL)ETHANONE

Chemical Property:

Vapor Pressure:2.34E-05mmHg at 25°C
Melting Point:112-113 °C
Refractive Index:1.672
Boiling Point:359.7 °C at 760 mmHg
Flash Point:171.3 °C
PSA：45.31000
Density:1.587 g/cm³
LogP:3.86640

Purity/Quality:

98%+ ^*data from raw suppliers

3-Acetyl-5-bromobenzo[b]thiophene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 20/21/22
Safety Statements: 24/25-36/37

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(5-BROMO-1-BENZOTHIEN-3-YL)ETHANONE

There total 5 articles about 1-(5-BROMO-1-BENZOTHIEN-3-YL)ETHANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 4923-87-9
5-bromobenzo[b]thiophene

: 108-24-7
acetic anhydride

: 1423-63-8
1-(5-bromobenzo[b]thiophen-3-yl)ethan-1-one

Guidance literature:: With trifluoroacetic acid; at 20 ℃; for 1.5h;
DOI:10.1016/j.tetlet.2018.01.026

Reference yield: 92.2%

: 4923-87-9
5-bromobenzo[b]thiophene

: 75-36-5
acetyl chloride

: 1423-63-8
1-(5-bromobenzo[b]thiophen-3-yl)ethan-1-one

Guidance literature:: acetyl chloride; With aluminum (III) chloride; In dichloromethane; at 0 ℃; for 0.5h;

5-bromobenzo[b]thiophene; In dichloromethane; at 25 ℃; for 2.5h;

Reference yield:

: 118780-12-4
1-bromo-4-[2,2-(dimethoxy)ethylsulfanyl]benzene

: 1423-63-8
1-(5-bromobenzo[b]thiophen-3-yl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 42.35 g / PPA / chlorobenzene / 15 h / Heating

2: 90 percent / SnCl₄ / 1,2-dichloro-ethane / 20 h / 0 - 20 °C

With tin(IV) chloride; In 1,2-dichloro-ethane; chlorobenzene; 2: Friedel-Crafts acylation;
DOI:10.1021/jm0205189