118780-12-4

Basic information

• Product Name: 1-BROMO-4-(2,2-DIMETHOXY-ETHYLSULFANYL)-BENZENE
• Synonyms: 1-BROMO-4-(2,2-DIMETHOXY-ETHYLSULFANYL)-BENZENE;(4-bromophenyl)(2,2-dimethoxyethyl)sulfane;Benzene, 1-broMo-4-[(2,2-diMethoxyethyl)thio]-
• CAS NO: 118780-12-4
• Molecular Formula: C₁₀H₁₃BrO₂S
• Molecular Weight: 277.17802
• EINECS: 200-258-5
• Mol File: 118780-12-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 313.994 °C at 760 mmHg
• Flash Point: 143.699 °C
• Appearance: cream
• Density: 1.413 g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-BROMO-4-(2,2-DIMETHOXY-ETHYLSULFANYL)-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMO-4-(2,2-DIMETHOXY-ETHYLSULFANYL)-BENZENE(118780-12-4)
• EPA Substance Registry System: 1-BROMO-4-(2,2-DIMETHOXY-ETHYLSULFANYL)-BENZENE(118780-12-4)

Safety Data

• Hazardous Substances Data: 118780-12-4(Hazardous Substances Data)

Usage

General Description

1-Bromo-4-(2,2-dimethoxy-ethylsulfanyl)-benzene is a chemical compound with the molecular formula C10H13BrO2S. It is a benzene derivative that contains a bromine atom and a 2,2-dimethoxy-ethylsulfanyl group attached to the benzene ring. 1-BROMO-4-(2,2-DIMETHOXY-ETHYLSULFANYL)-BENZENE is used in organic synthesis and pharmaceutical research as a building block for creating more complex molecules. It may also have potential applications in the development of new drugs or materials. Additionally, 1-Bromo-4-(2,2-dimethoxy-ethylsulfanyl)-benzene may have industrial uses in the production of fine chemicals or as a reagent in chemical reactions. However, as with any chemical, proper handling and safety protocols should be followed when working with this compound.

Upstream product

• 7252-83-7 1-bromo-2,2-dimethoxyethane 
• 106-53-6 para-bromobenzenethiol 

Downstream Products

• 193965-32-1 4-Fluorophenyl 5-Methoxy-2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl Ketone 
• 193965-31-0 5-methoxy-2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophene 
• 20532-30-3 5-methoxybenzothiophene 
• 306762-50-5 5-(4-butylsulfanylphenyl)-2-iodo-1-benzothiophene 
• 306762-47-0 5-bromo-2-(4-butylsulfanylphenyl)-1-benzothiophene 
• 306762-49-2 5-(4-butylsulfanylphenyl)-1-benzothiophene 
• 306762-46-9 5-bromo-2-iodo-1-benzothiophene 
• 331834-19-6 5-(4-heptyl-phenyl)-benzo[b]thiophene-2-carboxylic acid 
• 331834-20-9 5-(4-heptyl-phenyl)-benzo[b]thiophene-2-carboxylic acid amide 
• 331834-18-5 5-(4-heptyl-phenyl)-benzo[b]thiophene 
• 7312-24-5 5-bromobenzo[b]thiophene-3-carboxylic acid 
• 16304-39-5 5-hydroxybenzo[b]thiophene-3-carboxylic acid 
• 123392-43-8 5-methoxy-3-benzo[b]thiophenecarboxylic acid 
• 1423-63-8 1-(5-bromobenzo[b]thiophen-3-yl)ethan-1-one 

Relevant articles and documents

FARNESOID X RECEPTOR AGONISTS

The present invention relates to famesoid X receptors (FXR, NR1H4) FXR is a member of the nuclear receptor class of ligand-activate transcription factors More particularly, the present invention relates to compounds useful as agonists for FXR, pharmaceutical formulations comprising such compounds, and therapeutic use of the same Novel isoxazole compounds are disclosed as part of pharmaceutical compositions for the treatment of a condition mediated by decreased FXR activity, such as obesity, diabetes, cholestatic liver disease, liver fibrosis, and metabolic syndrome

The synthesis and transition temperatures of 2-(4-alkyl- and 4-alkoxy-phenyl)-5-cyano-1-benzofurans and related diaryl-1-benzofurans - An assessment of how deviations from linearity and conformational effects in a core unit affect mesogenicity

The synthesis and transition temperatures are reported for several 2-(4-alkyl- and 4-alkoxy-phenyl)-5-cyano-1-benzofurans, 2-(4′-alkylbiphenyl-4-yl)-5-cyano- and 5-(4′-alkylbiphenyl-4-yl)-2-cyano-1-benzofurans, and for compounds with other combinations of terminal alkyl and cyano groups in 2,5-disubstituted-1-benzofurans containing two phenyl units, some isolated examples of related cyclohexane systems are also presented. The mesogenic behaviour of these compounds and several intermediates (e.g. amides, acids and esters) is discussed and the transition temperatures are rationalised on the following basis (a) 1-benzofuran is a superior core unit to benzene, (b) 2,5-disubstitution in 1-benzofuran gives a bent core which adversely affects mesogenicity, to an extent which depends on its position in the core, (c) antiparallel associations in terminal cyano compounds can eliminate the disadvantage of a bent core structure, (d) 2-aryl-1-benzofurans have negligible inter-annular twist but 5-aryl-1-benzofurans have similar inter-annular twist to that in biphenyls.

UROKINASE INHIBITORS

Disclosed are benzothiophene and thienothiophene derivatives useful for inhibiting urokinase activity.