trans-N-benzyl-2,5-bis(ethoxycarbonyl)pyrrolidine

Base Information

Chemical Name:trans-N-benzyl-2,5-bis(ethoxycarbonyl)pyrrolidine
CAS No.:90290-04-3
Molecular Formula:C₁₇H₂₃NO₄
Molecular Weight:305.374
Hs Code.:

Synonyms:

Suppliers and Price of trans-N-benzyl-2,5-bis(ethoxycarbonyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of trans-N-benzyl-2,5-bis(ethoxycarbonyl)pyrrolidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of trans-N-benzyl-2,5-bis(ethoxycarbonyl)pyrrolidine

There total 3 articles about trans-N-benzyl-2,5-bis(ethoxycarbonyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 869-10-3
diethyl 2,5-dibromoadipate

: 100-46-9
benzylamine

: 52321-06-9
cis-1-benzylpyrrolidine-2,5-dicarboxylic acid diethyl ester

: 90290-04-3,50990-24-4,17740-40-8,52321-06-9,90365-12-1
trans-N-benzyl-2,5-bis(ethoxycarbonyl)pyrrolidine

Guidance literature:: With potassium carbonate; In water; toluene; at 80 ℃; for 24h;
DOI:10.1080/00397911.2018.1528615

Reference yield: 42.0%

: 17740-40-8
diethyl meso-1-benzyl-2,5-pyrrolidinedicarboxylate

: 90290-04-3,50990-24-4,17740-40-8,52321-06-9,90365-12-1
trans-N-benzyl-2,5-bis(ethoxycarbonyl)pyrrolidine

Guidance literature:: With water; sodium ethanolate; In ethanol; at 23 ℃; for 3h; selective hydrolysis of the cis isomer;
DOI:10.1021/jo00259a023

Reference yield:

: 52321-06-9
cis-1-benzylpyrrolidine-2,5-dicarboxylic acid diethyl ester

: 90290-04-3,50990-24-4,17740-40-8,52321-06-9,90365-12-1
trans-N-benzyl-2,5-bis(ethoxycarbonyl)pyrrolidine

Guidance literature:: With sodium ethanolate; In ethanol; at 23 ℃; for 12h; Product distribution; Thermodynamic data; epimerization; other 1-substituted cis-2,5-dicarbethoxypyrrolidines; ΔG⁰;
DOI:10.1021/jo00259a023