di-p-tolyl-carbamoyl chloride

Base Information

• Chemical Name: di-p-tolyl-carbamoyl chloride
• CAS No.: 55245-39-1
• Molecular Formula: C₁₅H₁₄ClNO
• Molecular Weight: 259.735
• Mol file: 55245-39-1.mol

Synonyms:

Chemical Property of di-p-tolyl-carbamoyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di-p-tolyl-carbamoyl chloride

There total 3 articles about di-p-tolyl-carbamoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosgene (75-44-5) + di-p-tolylamine (620-93-9) → di-p-tolyl-carbamoyl chloride (55245-39-1)

Guidance literature:

With sodium hydroxide; toluene; benzene;

Reference yield:

p-toluidine (106-49-0,12221-03-3) → di-p-tolyl-carbamoyl chloride (55245-39-1)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; triphenylphosphine; caesium carbonate / o-xylene / 12 h / 160 °C / Inert atmosphere

2: pyridine / dichloromethane / 0 - 20 °C

With pyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; triphenylphosphine; In dichloromethane; o-xylene;

DOI:10.1021/acs.joc.0c00659

Reference yield:

para-bromotoluene (106-38-7) → di-p-tolyl-carbamoyl chloride (55245-39-1)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; triphenylphosphine; caesium carbonate / o-xylene / 12 h / 160 °C / Inert atmosphere

2: pyridine / dichloromethane / 0 - 20 °C

With pyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; triphenylphosphine; In dichloromethane; o-xylene;

DOI:10.1021/acs.joc.0c00659

upstream raw materials:

phosgene

di-p-tolylamine

p-toluidine

para-bromotoluene

Downstream raw materials:

di-p-tolylcarbamoyl azide