N-(4-benzyloxyamino-6-chloro-pyrimidin-5-yl)-formimidic acid

Base Information

• Chemical Name: N-(4-benzyloxyamino-6-chloro-pyrimidin-5-yl)-formimidic acid
• CAS No.: 124077-21-0
• Molecular Formula: C₁₂H₁₁ClN₄O₂
• Molecular Weight: 278.698
• Mol file: 124077-21-0.mol

Synonyms:

Chemical Property of N-(4-benzyloxyamino-6-chloro-pyrimidin-5-yl)-formimidic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-benzyloxyamino-6-chloro-pyrimidin-5-yl)-formimidic acid

There total 2 articles about N-(4-benzyloxyamino-6-chloro-pyrimidin-5-yl)-formimidic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-benzyloxyamine (622-33-3) + 4,6-dichloro-5-formamidopyrimidine (123240-66-4) → N-(4-Benzyloxyamino-6-chloro-pyrimidin-5-yl)-formamide (124077-21-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In diethylene glycol dimethyl ether; at 100 ℃;

DOI:10.1016/0040-4039(90)80104-T

Reference yield:

N-benzyloxyamine (622-33-3) + N-(4,6-dichloropyrimidin-5-yl)formimidic acid → N-(4-benzyloxyamino-6-chloro-pyrimidin-5-yl)-formimidic acid (124077-21-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In diethylene glycol dimethyl ether;

DOI:10.1016/S0960-894X(00)00452-2

Reference yield:

N-(4-Benzyloxyamino-6-chloro-pyrimidin-5-yl)-formamide (124077-21-0) → 9-benzyloxy-6-chloropurine (124077-11-8)

Guidance literature:

With hydrogenchloride; orthoformic acid triethyl ester; In N,N-dimethyl-formamide; Yield given;

DOI:10.1016/0040-4039(90)80104-T

upstream raw materials:

N-benzyloxyamine

4,6-dichloro-5-formamidopyrimidine

Downstream raw materials:

9-benzyloxy-6-chloropurine

9-Benzyloxyadenine

9-benzyloxy-6-phthalimidopurine

9-benzyloxy-6-methoxy-9H-purine