2-Bromo-4'-formyldiphenyl ether

Base Information

• Chemical Name: 2-Bromo-4'-formyldiphenyl ether
• CAS No.: 86607-73-0
• Molecular Formula: C13H9 Br O2
• Molecular Weight: 277.117
• Mol file: 86607-73-0.mol

Synonyms:4-(2-Bromophenoxy)benzaldehyde

Chemical Property of 2-Bromo-4'-formyldiphenyl ether

Chemical Property:

• PSA: 26.30000
• LogP: 4.05390

Purity/Quality:

97% ^*data from raw suppliers

4-(2-Bromophenoxy)benzaldehyde 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Bromo-4'-formyldiphenyl ether

There total 2 articles about 2-Bromo-4'-formyldiphenyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-hydroxybromobenzene (95-56-7) + 4-nitrobenzaldehdye (555-16-8) → 2-Bromo-4'-formyldiphenyl ether (86607-73-0)

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 5h; Inert atmosphere; Schlenk technique; Green chemistry;

DOI:10.3184/174751917X15122516000113

Reference yield: 77.0%

2-hydroxybromobenzene (95-56-7) + 4-fluorobenzaldehyde (459-57-4) → 2-Bromo-4'-formyldiphenyl ether (86607-73-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl acetamide; at 170 ℃; for 4h;

DOI:10.1021/acs.orglett.9b00353

Reference yield: 92.0%

2-Bromo-4'-formyldiphenyl ether (86607-73-0) + trimethyl orthoformate (149-73-5) → C15H15BrO3

Guidance literature:

With toluene-4-sulfonic acid; In methanol; at 25 ℃; for 20h;

DOI:10.1021/acs.orglett.9b00353

upstream raw materials:

2-hydroxybromobenzene

4-fluorobenzaldehyde

4-nitrobenzaldehdye

Downstream raw materials:

2-Bromo-4'-hydroxymethyldiphenyl ether

(Z)-2-Benzoylamino-3-[4-(2-bromo-phenoxy)-phenyl]-acrylic acid methyl ester

(2Z)-2-(benzoylamino)-3-[4-(2-bromophenoxy)phenyl]prop-2-enoic acid

2-hydroxymethyl-dibenzo[b,d]furan