Benzoicacid, 4-[[4-amino-5-(2,6-difluorobenzoyl)-2-thiazolyl]amino]-, ethyl ester

Base Information

Chemical Name:Benzoicacid, 4-[[4-amino-5-(2,6-difluorobenzoyl)-2-thiazolyl]amino]-, ethyl ester
CAS No.:486413-80-3
Molecular Formula:C19H15 F2 N3 O3 S
Molecular Weight:403.409
Hs Code.:

Synonyms:4-[[4-Amino-5-(2,6-difluorobenzoyl)thiazol-2-yl]amino]benzoicacid Ethyl Ester

Suppliers and Price of Benzoicacid, 4-[[4-amino-5-(2,6-difluorobenzoyl)-2-thiazolyl]amino]-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 2 raw suppliers

Chemical Property of Benzoicacid, 4-[[4-amino-5-(2,6-difluorobenzoyl)-2-thiazolyl]amino]-, ethyl ester

Chemical Property:

PSA：122.55000
LogP:4.80900

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Technology Process of Benzoicacid, 4-[[4-amino-5-(2,6-difluorobenzoyl)-2-thiazolyl]amino]-, ethyl ester

There total 1 articles about Benzoicacid, 4-[[4-amino-5-(2,6-difluorobenzoyl)-2-thiazolyl]amino]-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 420-04-2
CYANAMID

: 1205-06-7
4-ethoxycarbonylphenyl isothiocyanate

: 56159-89-8
2-bromo-1-(2,6-difluorophenyl)ethanone

: 486413-80-3
4-[4-amino-5-(2,6-difluoro-benzoyl)-thiazol-2-ylamino]-benzoic acid ethyl ester

Guidance literature:: CYANAMID; 4-ethoxycarbonylphenyl isothiocyanate; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 0 - 2.6 ℃; for 2.2h;

2-bromo-1-(2,6-difluorophenyl)ethanone; In acetonitrile; at 0 - 20 ℃;

Reference yield: 91.0%

: 486413-80-3
4-[4-amino-5-(2,6-difluoro-benzoyl)-thiazol-2-ylamino]-benzoic acid ethyl ester

: 486413-81-4
4-{4-Amino-5-[1-(2,6-difluorophenyl)-methanoyl]-thiazol-2-ylamino}-benzoic acid

Guidance literature:: 4-[4-amino-5-(2,6-difluoro-benzoyl)-thiazol-2-ylamino]-benzoic acid ethyl ester; With sodium hydroxide; water; In methanol; at 20 - 31 ℃;

With hydrogenchloride; In water; at 5 ℃; pH=4.0;