5-Chloro-1,6-naphthyridine

Base Information

Chemical Name:5-Chloro-1,6-naphthyridine
CAS No.:23616-32-2
Molecular Formula:C8H5ClN2
Molecular Weight:164.594
Hs Code.:2933990090
European Community (EC) Number:672-893-0
DSSTox Substance ID:DTXSID70480355
Wikidata:Q82315067
Mol file:23616-32-2.mol

Synonyms:5-Chloro-1,6-naphthyridine;23616-32-2;5-Chloro[1,6]naphthyridine;5-chloro-[1,6]naphthyridine;1,6-Naphthyridine, 5-chloro-;MFCD01646205;SCHEMBL523735;DTXSID70480355;WXAOVVFKLPOPAM-UHFFFAOYSA-N;BCP08210;YAA61632;AKOS006276186;PB32262;DS-11174;SY017340;AM20050980;CS-0012633;FT-0645426;EN300-295335;A816805;J-517230;5-chloro-1,6-naphthyridine

Suppliers and Price of 5-Chloro-1,6-naphthyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-chloro-1,6-naphthyridine
50mg
$ 45.00

SynQuest Laboratories
5-Chloro-1,6-naphthyridine 95.0%
1 g
$ 224.00

SynQuest Laboratories
5-Chloro-1,6-naphthyridine 95.0%
5 g
$ 888.00

SynQuest Laboratories
5-Chloro-1,6-naphthyridine 95.0%
10 g
$ 1536.00

Medical Isotopes, Inc.
5-Chloro[1,6]naphthyridine 95+%
5 g
$ 1245.00

Medical Isotopes, Inc.
5-Chloro[1,6]naphthyridine 95+%
1 g
$ 600.00

Matrix Scientific
5-Chloro-1,6-naphthyridine
500mg
$ 352.00

Crysdot
5-Chloro[1,6]naphthyridine 95+%
5g
$ 588.00

AstaTech
5-CHLORO-1,6-NAPHTHYRIDINE 97%
0.25 / G
$ 85.00

AstaTech
5-CHLORO-1,6-NAPHTHYRIDINE 97%
1 / G
$ 190.00

Total 49 raw suppliers

Chemical Property of 5-Chloro-1,6-naphthyridine

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Melting Point:106-107℃
Refractive Index:1.663
Boiling Point:307.889 °C at 760 mmHg
PKA:2.04±0.30(Predicted)
Flash Point:168.825 °C
PSA：25.78000
Density:1.35 g/cm³
LogP:2.28320
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:164.0141259
Heavy Atom Count:11
Complexity:140

Purity/Quality:

97% ^*data from raw suppliers

5-chloro-1,6-naphthyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CN=C2Cl)N=C1

Technology Process of 5-Chloro-1,6-naphthyridine

There total 8 articles about 5-Chloro-1,6-naphthyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 23616-31-1
1,6-naphthyridine-5(6H)-one

: 23616-32-2
5-chloro-[1,6]naphthyridine

Guidance literature:: 1,6-naphthyridine-5(6H)-one; With trichlorophosphate; at 100 ℃; for 14h;

With sodium carbonate; In dichloromethane; water; at 0 ℃; pH=6 - 7; Product distribution / selectivity;

Reference yield:

: 97308-49-1
2-trimethylsilylethynyl-3-pyridinecarbonitrile

: 23616-32-2
5-chloro-[1,6]naphthyridine

Guidance literature:: Multi-step reaction with 4 steps

1.1: 14 h / 80 °C / Inert atmosphere

2.1: sodium carbonate; dihydrogen peroxide / water; acetone / 14 h / 20 °C

3.1: toluene-4-sulfonic acid / toluene / 14 h / Reflux

4.1: trichlorophosphate / 14 h / 100 °C

4.2: 0 °C / pH 6 - 7

With dihydrogen peroxide; sodium carbonate; trichlorophosphate; toluene-4-sulfonic acid; In water; acetone; toluene;

Reference yield:

: 97308-52-6
2-(β,β-dimethoxyethyl)-3-pyridinecarbonitrile

: 23616-32-2
5-chloro-[1,6]naphthyridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium carbonate; dihydrogen peroxide / water; acetone / 14 h / 20 °C

2.1: toluene-4-sulfonic acid / toluene / 14 h / Reflux

3.1: trichlorophosphate / 14 h / 100 °C

3.2: 0 °C / pH 6 - 7

With dihydrogen peroxide; sodium carbonate; trichlorophosphate; toluene-4-sulfonic acid; In water; acetone; toluene;