5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one

Base Information

Chemical Name:5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one
CAS No.:304468-42-6
Molecular Formula:C13H14 Br N O
Molecular Weight:280.164
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30467006
Wikidata:Q82293746
Mol file:304468-42-6.mol

Synonyms:304468-42-6;5'-BROMOSPIRO[CYCLOHEXANE-1,3'-INDOLIN]-2'-ONE;5'-bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one;5'-Bromospiro[cyclohexane-1,3'-indol]-2'(1'H)-one;5-bromospiro[1H-indole-3,1'-cyclohexane]-2-one;Spiro[cyclohexane-1,3'-[3H]indol]-2'(1'H)-one, 5'-bromo-;SCHEMBL61843;DTXSID30467006;MOCOBMQLHAVEMT-UHFFFAOYSA-N;Spiro[cyclohexane-1,3'-[3H]indol]-2'(1'H)-one,5'-bromo-;MFCD12964079;AKOS005073422;LD-0097;SB64418;CS-0107259;FT-0646109;EN300-79335;5'-bromo-spiro[cyclohexane-1,3'-indolin]-2'-one;J-517211;5`-Bromospiro[cyclohexane-1,3`-indol]-2`(1`H)-one;Z1210584854;5'-bromospiro[cyclohexane-1,3'-[3H]indol]-2'(1'H)-one;5'-Bromospiro [cyclohexane-1,3'-[3H] indol]-2'(1 'H)-one;5'-Bromospiro[cyclohexane-1,3'-[3H]indol]-2' (1'H)-one

Suppliers and Price of 5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one >95%
500mg
$ 340.00

Matrix Scientific
5'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one >95%
5g
$ 1525.00

Matrix Scientific
5'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one >95%
1g
$ 534.00

Crysdot
5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one 97%
1g
$ 504.00

Crysdot
5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one 97%
5g
$ 1515.00

Chemenu
5''-Bromo-1'',2''-dihydrospiro[cyclohexane-1,3''-indole]-2''-one 97%
5g
$ 1428.00

Chemenu
5''-Bromo-1'',2''-dihydrospiro[cyclohexane-1,3''-indole]-2''-one 97%
1g
$ 476.00

Alichem
5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one
1g
$ 714.96

Alichem
5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one
5g
$ 1527.00

AK Scientific
5'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one
5g
$ 2108.00

Total 13 raw suppliers

Chemical Property of 5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one

Chemical Property:

Melting Point:196-199 °C
Boiling Point:430.895oC at 760 mmHg
PKA:13.16±0.20(Predicted)
Flash Point:214.398oC
PSA：29.10000
Density:1.512g/cm3
LogP:3.74110
Storage Temp.:2-8°C
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:279.02588
Heavy Atom Count:16
Complexity:298

Purity/Quality:

97% ^*data from raw suppliers

5'-Bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2(CC1)C3=C(C=CC(=C3)Br)NC2=O

Technology Process of 5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one

There total 6 articles about 5'-Bromospiro[cyclohexane-1,3'-indolin]-2'-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 111-24-0
1,5-dibromo-pentane

: 20870-78-4
5-bromo-2-indolin-2-one

: 304468-42-6
5'-bromospiro[cyclohexane-1,3'-[3H]indol]-2'(1'H)-one

Guidance literature:: 5-bromo-2-indolin-2-one; With potassium tert-butylate; In tetrahydrofuran; at -15 ℃; for 0.5h;

1,5-dibromo-pentane; In tetrahydrofuran; at 0 ℃; for 1h;
DOI:10.1080/00304940509354961