ETHYL 2-CHLORO-3-NITROBENZOATE

Base Information

• Chemical Name: ETHYL 2-CHLORO-3-NITROBENZOATE
• CAS No.: 3979-45-1
• Molecular Formula: C9H8 Cl N O4
• Molecular Weight: 229.62
• Mol file: 3979-45-1.mol

Synonyms:Ethyl2-chloro-3-nitrobenzoate

Chemical Property of ETHYL 2-CHLORO-3-NITROBENZOATE

Chemical Property:

• PSA: 72.12000
• LogP: 2.94810

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-3-nitro-benzoicacidethylester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL 2-CHLORO-3-NITROBENZOATE

There total 2 articles about ETHYL 2-CHLORO-3-NITROBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethanol (64-17-5) + 2-chloro-3-nitrobezoic acid (3970-35-2) → ethyl 2-chloro-3-nitrobenzoate (3979-45-1)

Guidance literature:

With sulfuric acid; at 15 - 30 ℃; for 24h; Heating / reflux;

Reference yield:

2-chloro-3-nitrobezoic acid (3970-35-2) → ethyl 2-chloro-3-nitrobenzoate (3979-45-1)

Guidance literature:

2-chloro-3-nitrobezoic acid; With thionyl chloride; In ethanol; for 5h; Cooling with ice;

With hydrogenchloride; iron; In ethanol; water; at 60 ℃; for 3h;

Reference yield: 97.0%

ethyl 2-chloro-3-nitrobenzoate (3979-45-1) → ethyl 3-amino-2-chlorobenzoate (1261671-67-3)

Guidance literature:

With iron; acetic acid; at 20 - 22 ℃; for 18h;

upstream raw materials:

ethanol

2-chloro-3-nitrobezoic acid

Downstream raw materials:

7-nitro-indazolin-3-one

7-nitro-2-phenyl-1,2-dihydro-3H-indazol-3-one

2-<(5-chloro-2-methylphenyl)thio>-3-nitrobenzoic acid

5-amino-1-<<2-(diethylamino)ethyl>amino>-4-methylthioxanthenone