(3-Chlorophenyl)carbamic chloride

Base Information

• Chemical Name: (3-Chlorophenyl)carbamic chloride
• CAS No.: 51028-36-5
• Molecular Formula: C7H5Cl2NO
• Molecular Weight: 190.029
• Hs Code.: 2903999090
• Mol file: 51028-36-5.mol

Synonyms:(3-Chlor-phenyl)-carbamidsaeure-sec-butylester;BCPC [ISO];(3-chloro-phenyl)-carbamic acid sec-butyl ester;sec-Butyl N-(3-chlorophenyl)carbamate;Carbanilic acid,sec-butyl ester;BCPC;<3-Chlor-phenyl>-carbamoylchlorid;

Chemical Property of (3-Chlorophenyl)carbamic chloride

Chemical Property:

• PSA: 29.10000
• Density: 1.469
• LogP: 3.18370

Purity/Quality:

98%Min ^*data from raw suppliers

(3-Chlorophenyl)carbamicchloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3-Chlorophenyl)carbamic chloride

There total 2 articles about (3-Chlorophenyl)carbamic chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosgene (75-44-5) + 3-chloro-aniline (108-42-9) → <3-Chlor-phenyl>-carbamoylchlorid (51028-36-5)

Guidance literature:

In dichloromethane; toluene; at 0 ℃; for 0.25h;

DOI:10.1021/jm960853v

Reference yield:

m-chlorophenyl isocyanate (2909-38-8) → <3-Chlor-phenyl>-carbamoylchlorid (51028-36-5)

Guidance literature:

With hydrogenchloride;

Reference yield:

<3-Chlor-phenyl>-carbamoylchlorid (51028-36-5) → m-chlorophenyl isocyanate (2909-38-8)

Guidance literature:

With triethylamine; In dichloromethane; toluene; for 0.25h;

DOI:10.1021/jm960853v

upstream raw materials:

m-chlorophenyl isocyanate

phosgene

3-chloro-aniline

Downstream raw materials:

m-chlorophenyl isocyanate

Refernces

• 1、 Soulier, Jean-Louis,Yang, Donglai,Brémont, Béatrice,Croci, Tiziano,Guzzi, Umberto,Langlois, Michel. "Arylcarbamate derivatives of 1-piperidineethanol as potent ligands for 5-HT4 receptors". . p. 1755 - 1761. Retrieved 2007/10/03.