C₁₃H₁₆BrNO

Base Information

• Chemical Name: C₁₃H₁₆BrNO
• CAS No.: 1448600-33-6
• Molecular Formula: C₁₃H₁₆BrNO
• Molecular Weight: 282.18
• Mol file: 1448600-33-6.mol

Synonyms:

Chemical Property of C₁₃H₁₆BrNO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₃H₁₆BrNO

There total 2 articles about C₁₃H₁₆BrNO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C7H11ClO + 2-bromoaniline (615-36-1) → C13H16BrNO (1448600-33-6)

Guidance literature:

C₇H₁₁ClO; 2-bromoaniline; With triethylamine; In dichloromethane; at 0 ℃; for 0.0833333h; Inert atmosphere;

With dmap; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1002/anie.201207959

Reference yield:

1-(1-Methylethyl)cyclopropancarbonsaeure (104131-92-2) → C13H16BrNO (1448600-33-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 0 - 20 °C / Inert atmosphere

2.1: triethylamine / dichloromethane / 0.08 h / 0 °C / Inert atmosphere

2.2: 20 °C / Inert atmosphere

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;

DOI:10.1002/anie.201207959

Reference yield:

C13H16BrNO (1448600-33-6) → N-(2-bromophenyl)-1,1,1-trifluoro-N-((1-isopropylcyclopropyl)methyl)methanesulfonamide (1448599-99-2)

Guidance literature:

Multi-step reaction with 2 steps

1: borane-THF / tetrahydrofuran / 8 h / Reflux; Inert atmosphere

2: sodium hydride / 1,2-dichloro-ethane / 0 - 20 °C / Inert atmosphere

With borane-THF; sodium hydride; In tetrahydrofuran; 1,2-dichloro-ethane;

DOI:10.1002/anie.201207959

upstream raw materials:

1-(1-Methylethyl)cyclopropancarbonsaeure

2-bromoaniline

Downstream raw materials:

N-(2-bromophenyl)-1,1,1-trifluoro-N-((1-isopropylcyclopropyl)methyl)methanesulfonamide

C₁₃H₁₈BrN

Refernces