6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine

Base Information

Chemical Name:6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine
CAS No.:133111-56-5
Molecular Formula:C21H20 Cl N
Molecular Weight:321.85
Hs Code.:2933990090
DSSTox Substance ID:DTXSID20433194
Nikkaji Number:J2.618.934I
Wikidata:Q82247321
ChEMBL ID:CHEMBL1689593
Mol file:133111-56-5.mol

Synonyms:133111-56-5;6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine;6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-1,3-dihydropyrrolizine;6-(4-Chlorophenyl)-2,3-Dihydro-2,2-Dimethyl-7-Phenyl-1H-Pyrrolizine;1H-Pyrrolizine, 6-(4-chlorophenyl)-2,3-dihydro-2,2-dimethyl-7-phenyl-;SCHEMBL1839904;CHEMBL1689593;DTXSID20433194;AKOS015909801;FT-0706532;1-Phenyl-2-(4-chlorophenyl)-6,6-dimethyl-6,7-dihydro-5H-pyrrolizine

Suppliers and Price of 6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine 95+%
1g
$ 1647.00

Matrix Scientific
6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine 95+%
250mg
$ 742.00

Crysdot
6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine 95+%
1g
$ 772.00

American Custom Chemicals Corporation
6-(4-CHLOROPHENYL)-2,2-DIMETHYL-7-PHENYL-2,3-DIHYDRO-1H-PYRROLIZINE 95.00%
5MG
$ 503.17

Alichem
6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine
1g
$ 659.40

AK Scientific
6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine
250mg
$ 1051.00

Total 46 raw suppliers

Chemical Property of 6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine

Chemical Property:

PSA：4.93000
LogP:6.05780
Storage Temp.:2-8°C
XLogP3:5.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:2
Exact Mass:321.1284273
Heavy Atom Count:23
Complexity:406

Purity/Quality:

99% ^*data from raw suppliers

6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(CC2=C(C(=CN2C1)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C

Technology Process of 6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine

There total 15 articles about 6-(4-Chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 536-38-9
4-chlorobenzoylmethyl bromide

: 116673-95-1
5-benzyl-3,3-dimethyl-3,4-dihydro-2H-pyrrole

: 133111-56-5
6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine

Guidance literature:: 5-benzyl-3,3-dimethyl-3,4-dihydro-2H-pyrrole; With sodium hydrogencarbonate; In methanol;

4-chlorobenzoylmethyl bromide; In methanol; for 20h;

With water; at 40 ℃; for 1h;
DOI:10.1135/cccc2009026

Reference yield: 15.0%

: 1679-18-1
4-Chlorophenylboronic acid

: 226900-28-3
2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizin-6-yl trifluoromethanesulfonate

: 133111-56-5
6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1H-pyrrolizine

Guidance literature:: With potassium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1) rt, overnight; 2) reflux, 24 h;
DOI:10.1016/S0040-4020(99)00176-3