R 74714

Base Information Edit

Chemical Name:R 74714
CAS No.:119365-25-2
Molecular Formula:C₂₂H₂₅F₂NO₄
Molecular Weight:405.442
Hs Code.:
Mol file:119365-25-2.mol

Synonyms:

Suppliers and Price of R 74714

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
R74714
1mg
$ 638.00

TRC
R74714
10mg
$ 2625.00

TRC
R74714
1mg
$ 290.00

Medical Isotopes, Inc.
R74714
10 mg
$ 3500.00

American Custom Chemicals Corporation
NEBIVOLOL IMPURITY B 95.00%
5MG
$ 505.05

Total 2 raw suppliers

Chemical Property of R 74714 Edit

Chemical Property:

Purity/Quality:

95%-98% ^*data from raw suppliers

R74714 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses R 74714 is a potential agonist and blocker of the β2 adrenergic receptor and have been profiled as an isomer of Nebivolol (N387900), an antihypertensive agent.

Technology Process of R 74714

There total 64 articles about R 74714 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 1224567-85-4
l-(R,S,S,S)-benzyl nebivolol hydrochloride

: 118457-16-2,118457-14-0,118457-15-1,119365-25-2,119365-23-0,1360598-84-0
nebivolol

Guidance literature:: l-(R,S,S,S)-benzyl nebivolol hydrochloride; With sodium hydroxide; In water; iso-butanol; at 25 ℃; Inert atmosphere;

With formic acid; 5% Pd(II)/C(eggshell); In iso-butanol; at 70 ℃; for 4h;

With sodium hydroxide; In water; iso-butanol;

Reference yield: 62.0%

: 682359-63-3
N-[(S,S)-1-hydroxy-2-(6-fluoro-chroman-4-one-2-yl)]-N-[(R,S)-1-hydroxy-2-(6-fiuoro-chroman-4-one-2-yl)]-amine

: 118457-16-2,118457-14-0,118457-15-1,119365-25-2,119365-23-0,1360598-84-0
nebivolol

Guidance literature:: N-[(S,S)-1-hydroxy-2-(6-fluoro-chroman-4-one-2-yl)]-N-[(R,S)-1-hydroxy-2-(6-fiuoro-chroman-4-one-2-yl)]-amine; With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In ethanol; water; at 50 - 55 ℃; for 16h; under 2250.23 Torr;

With sodium hydrogencarbonate; In water; pH=8;