Substance P (7-11)

Base Information

Chemical Name:Substance P (7-11)
CAS No.:51165-05-0
Molecular Formula:C31H44N6O5S
Molecular Weight:612.78300
Hs Code.:
DSSTox Substance ID:DTXSID70965435
Nikkaji Number:J274.731F
Wikidata:Q82947629
Mol file:51165-05-0.mol

Synonyms:SP(7-11);substance P (7-11)

Suppliers and Price of Substance P (7-11)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
Substance P (7-11)
25mg
$ 280.00

ChemScene
Substance P (7-11)
10mg
$ 140.00

ChemScene
Substance P (7-11)
5mg
$ 80.00

American Custom Chemicals Corporation
SUBSTANCE P (7 - 11) 95.00%
5MG
$ 1008.00

American Custom Chemicals Corporation
SUBSTANCE P (7 - 11) 95.00%
2MG
$ 704.00

American Custom Chemicals Corporation
SUBSTANCE P (7 - 11) 95.00%
1MG
$ 579.00

Alfa Aesar
Substance P (7-11)
1mg
$ 39.70

Total 22 raw suppliers

Chemical Property of Substance P (7-11)

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1003.3oC at 760 mmHg
PKA:13.26±0.46(Predicted)
Flash Point:560.6oC
PSA：210.81000
Density:1.207g/cm3
LogP:3.61840
Storage Temp.:-15°C
XLogP3:2.1
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:18
Exact Mass:612.30938970
Heavy Atom Count:43
Complexity:907

Purity/Quality:

99%, ^*data from raw suppliers

Substance P (7-11) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)NC(CCSC)C(=O)N)NC(=O)CNC(=O)C(CC1=CC=CC=C1)NC(=O)C(CC2=CC=CC=C2)N
Isomeric SMILES:CC(C)C[C@@H](C(=O)N[C@@H](CCSC)C(=O)N)NC(=O)CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=CC=C2)N

Technology Process of Substance P (7-11)

There total 9 articles about Substance P (7-11) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73148-99-9
N-t-Boc-Phe-Phe-Gly-Leu-Met-NH₂

: 51165-05-0,78081-73-9
H-Phe-Phe-Gly-Leu-Met-NH₂

Guidance literature:: With methoxybenzene; trifluoroacetic acid; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1016/0223-5234(88)90006-2

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 51165-05-0,78081-73-9
H-Phe-Phe-Gly-Leu-Met-NH₂

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / NMM, IBCF / dimethylformamide / -15 °C

2: 85 percent / 1N NaOH / dioxane; methanol / 0 deg C, 5 h, RT

3: 54.6 percent / IBCF, NMMole / dimethylformamide / -20 °C

4: TFA, anisole / CH₂Cl₂ / 1 h / 0 °C

With 4-methyl-morpholine; sodium hydroxide; methoxybenzene; trifluoroacetic acid; isobutyl chloroformate; In 1,4-dioxane; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(88)90006-2

Reference yield:

: 13139-15-6,53296-34-7
N-tert-butoxycarbonyl-L-leucine

: 51165-05-0,78081-73-9
H-Phe-Phe-Gly-Leu-Met-NH₂

Guidance literature:: Multi-step reaction with 4 steps

1: 93.6 percent / NMM, IBCF / dimethylformamide / -20 °C

2: TFA, anisole / CH₂Cl₂ / 1 h / 0 °C

3: 54.6 percent / IBCF, NMMole / dimethylformamide / -20 °C

4: TFA, anisole / CH₂Cl₂ / 1 h / 0 °C

With 4-methyl-morpholine; methoxybenzene; trifluoroacetic acid; isobutyl chloroformate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(88)90006-2