1-Bromo-2-[2-(2-bromophenyl)ethyl]benzene

Base Information

• Chemical Name: 1-Bromo-2-[2-(2-bromophenyl)ethyl]benzene
• CAS No.: 59485-34-6
• Molecular Formula: C14H12 Br2
• Molecular Weight: 340.057
• European Community (EC) Number: 261-783-4
• NSC Number: 140278
• DSSTox Substance ID: DTXSID10974889
• Nikkaji Number: J298.172F
• Wikidata: Q82959351
• Mol file: 59485-34-6.mol

Synonyms:59485-34-6;1,2-Bis(2-bromophenyl)ethane;1-Bromo-2-[2-(2-bromophenyl)ethyl]benzene;o,o'-Dibromobibenzyl;EINECS 261-783-4;Benzene, 1,1'-(1,2-ethanediyl)bis[2-bromo-;Bibenzyl, 2,2'-dibromo-;1,1'-Ethylenebis(2-bromobenzene);NSC140278;2,2'-dibromobibenzyl;1,1'-(1,2-Ethanediyl)bis(2-bromobenzene);C(Cc1ccccc1Br)c2ccccc2Br;SCHEMBL6738136;DTXSID10974889;MFCD00196991;AKOS024322362;NSC 140278;NSC-140278;1,1'-(Ethane-1,2-diyl)bis(2-bromobenzene);1-Bromo-2-[2-(2-bromophenyl)ethyl]benzene #;F13204

Chemical Property of 1-Bromo-2-[2-(2-bromophenyl)ethyl]benzene

Chemical Property:

• Melting Point: 84.5 °C
• Boiling Point: 150-170 °C(Press: 0.01 Torr)
• Flash Point: 199.4oC
• PSA: 0.00000
• Density: 1.579±0.06 g/cm3(Predicted)
• LogP: 4.99680
• XLogP3: 5.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 339.92853
• Heavy Atom Count: 16
• Complexity: 183

Purity/Quality:

99% ^*data from raw suppliers

1,2-Bis(2-bromophenyl)ethane 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)CCC2=CC=CC=C2Br)Br

Technology Process of 1-Bromo-2-[2-(2-bromophenyl)ethyl]benzene

There total 25 articles about 1-Bromo-2-[2-(2-bromophenyl)ethyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2-bromobenzylzinc(II) bromide (307496-27-1) → 1,2-bis(2-bromophenyl)ethane (59485-34-6)

Guidance literature:

With Desyl chloride; dichloro[2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]palladium(II); In tetrahydrofuran; at 60 ℃;

DOI:10.1021/ol0258536

Reference yield: 89.0%

2-methylphenyl bromide (95-46-5) → 1,2-bis(2-bromophenyl)ethane (59485-34-6)

Guidance literature:

With di-tert-butyl peroxide; sodium acetate; at 120 ℃; for 10h; Schlenk technique; Green chemistry;

DOI:10.1002/adsc.201701389

Reference yield: 61.2%

4-chlorobenzanilide (6833-15-4) → 1,2-bis(2-bromophenyl)ethane (59485-34-6) + 2-bromo-4-chloro-N-phenylbenzamide

Guidance literature:

With n-butyllithium; 1-Bromo-2-bromomethyl-benzene; In tetrahydrofuran; 1.) -78 deg C, 0.5 h; r.t., 1 h, 2.) -78 deg C, 1 h; r.t., 1 h;

DOI:10.1007/BF00817261

upstream raw materials:

toluene-4-sulfonic acid-[N',N'-bis-(2-bromo-benzyl)-hydrazide]

N,N-bis-(2-bromo-benzyl)-hydrazine

phenyllithium

1-Bromo-2-bromomethyl-benzene

Downstream raw materials:

2-(10,11-dihydro-dibenzo[b,f]borepin-5-yloxy)-ethylamine

5-phenyl-10,11-dihydro-5H-dibenzo[b,f]phosphepine

5-methoxy-5-phenyl-10,11-dihydro-5H-dibenzo[b,f]silepine

5,5-diphenyl-10,11-dihydro-5H-dibenzo[b,f]silepine