(4-(2-chlorophenyl)thiazol-2-yl)Methanol

Base Information

• Chemical Name: (4-(2-chlorophenyl)thiazol-2-yl)Methanol
• CAS No.: 1050507-07-7
• Molecular Formula: C10H8ClNOS
• Molecular Weight: 225.699
• Hs Code.: 2934100090
• Mol file: 1050507-07-7.mol

Synonyms:[4-(2-Chlorophenyl)thiazol-2-yl]methanol;[4-(2-Chlorophenyl)-1,3-thiazol-2-yl]methanol;

Chemical Property of (4-(2-chlorophenyl)thiazol-2-yl)Methanol

Chemical Property:

• Boiling Point: 360.6 °C at 760 mmHg
• PKA: 12.98±0.10(Predicted)
• Flash Point: 171.9 °C
• PSA: 61.36000
• Density: 1.383 g/cm³
• LogP: 2.95580

Purity/Quality:

98%min ^*data from raw suppliers

(4-(2-Chlorophenyl)thiazol-2-yl)methanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-(2-chlorophenyl)thiazol-2-yl)Methanol

There total 2 articles about (4-(2-chlorophenyl)thiazol-2-yl)Methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chlorophenacyl bromide (5000-66-8) → (4-(2-chlorophenyl)thiazol-2-yl)methanol (1050507-07-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: ethanol / 6 h / Heating / reflux

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.67 h / 0 °C

2.2: 0 °C

With lithium aluminium tetrahydride; In tetrahydrofuran; ethanol;

Reference yield:

ethyl 4-(2-chlorophenyl)thiazole-2-carboxylate (1050507-06-6) → (4-(2-chlorophenyl)thiazol-2-yl)methanol (1050507-07-7)

Guidance literature:

ethyl 4-(2-chlorophenyl)thiazole-2-carboxylate; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 0.666667h;

With water; sodium sulfate; In tetrahydrofuran; at 0 ℃;

Reference yield:

(4-(2-chlorophenyl)thiazol-2-yl)methanol (1050507-07-7) + methanesulfonyl chloride (124-63-0) → (4-(2-chlorophenyl)thiazol-2-yl)methyl methanesulfonate (1050507-05-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h;

upstream raw materials:

ethyl 4-(2-chlorophenyl)thiazole-2-carboxylate

2-chlorophenacyl bromide

Downstream raw materials:

(4-(2-chlorophenyl)thiazol-2-yl)methyl methanesulfonate

{4-[4-(2-chloro-phenyl)-thiazol-2-ylmethoxy]-2-methyl-phenoxy}-acetic acid methyl ester

{4-[4-(2-chloro-phenyl)-thiazol-2-ylmethoxy]-2-methyl-phenoxy}-acetic acid

6-{[4-(2-chloro-phenyl)-thiazol-2-ylmethyl]-amino}-naphthalene-2-carboxylic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1050507-07-7 (4-(2-chlorophenyl)thiazol-2-yl)Methanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send