l-cystine dimethyl ester dihydrochloride

Base Information

• Chemical Name: l-cystine dimethyl ester dihydrochloride
• CAS No.: 110970-86-0
• Molecular Formula: C₈H₁₆N₂O₄S₂*2ClH
• Molecular Weight: 341.28
• Mol file: 110970-86-0.mol

Synonyms:

Chemical Property of l-cystine dimethyl ester dihydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of l-cystine dimethyl ester dihydrochloride

There total 1 articles about l-cystine dimethyl ester dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methanol (67-56-1) + S,S-cystine (349-46-2) → l-cystine dimethyl ester dihydrochloride (18598-59-9,22888-38-6,32854-09-4,110970-86-0,144000-36-2)

Guidance literature:

With thionyl chloride; at 0 - 20 ℃;

Reference yield:

trityl chloride (76-83-5) + l-cystine dimethyl ester dihydrochloride (18598-59-9,22888-38-6,32854-09-4,110970-86-0,144000-36-2) → N,N'-ditrityl-D-cystine dimethyl ester (18598-60-2,144000-37-3)

Guidance literature:

With triethylamine; In chloroform; for 24h; Ambient temperature;

Reference yield:

N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) + l-cystine dimethyl ester dihydrochloride (18598-59-9,22888-38-6,32854-09-4,110970-86-0,144000-36-2) → (S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-phenyl-propionylamino)-2-methoxycarbonyl-ethyldisulfanyl]-propionic acid methyl ester

Guidance literature:

With 4-methyl-morpholine; dicyclohexyl-carbodiimide; In chloroform; at 20 ℃;

DOI:10.1021/jo000738z

upstream raw materials:

methanol

S,S-cystine

Downstream raw materials:

N,N'-ditrityl-D-cystine dimethyl ester