4-(3,5-Dibromophenyl)-2,6-diphenylpyrimidine

Base Information

• Chemical Name: 4-(3,5-Dibromophenyl)-2,6-diphenylpyrimidine
• CAS No.: 607740-08-9
• Molecular Formula: C22H14Br2N2
• Molecular Weight: 466.175
• Hs Code.: 2933599090
• Mol file: 607740-08-9.mol

Synonyms:Pyrimidine, 4-(3,5-dibromophenyl)-2,6-diphenyl-; 4-(3,5-dibromo-phenyl)-2,6-diphenyl-pyrimidine

Chemical Property of 4-(3,5-Dibromophenyl)-2,6-diphenylpyrimidine

Chemical Property:

• Melting Point: 197.0 to 201.0 °C
• Boiling Point: 476.7±45.0 °C(Predicted)
• PKA: -0.65±0.41(Predicted)
• PSA: 25.78000
• Density: 1.532
• LogP: 7.00260
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

4-(3,5-Dibromophenyl)-2,6-diphenylpyrimidine >98.0%(HPLC)(N) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(3,5-Dibromophenyl)-2,6-diphenylpyrimidine

There total 3 articles about 4-(3,5-Dibromophenyl)-2,6-diphenylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.4%

3,5-dibromobenzaldehyde (56990-02-4) + benzamidine monohydrochloride (1670-14-0) + acetophenone (98-86-2) → 4-(3,5-dibromo-phenyl)-2,6-diphenyl-pyrimidine (607740-08-9)

Guidance literature:

3,5-dibromobenzaldehyde; acetophenone; With sodium hydroxide; In ethanol; at 20 ℃; for 8h;

benzamidine monohydrochloride; In ethanol; for 8h; Reflux;

Reference yield: 45.0%

→ 4-(3,5-dibromo-phenyl)-2,6-diphenyl-pyrimidine (607740-08-9)

Guidance literature:

Reference yield: 30.0%

4-chloro-2,6-diphenyl-1,3-pyrimidine (29509-91-9) + 3,5-dibromophenylboronic acid (117695-55-3) → 4-(3,5-dibromo-phenyl)-2,6-diphenyl-pyrimidine (607740-08-9)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In tetrahydrofuran; water; for 12h; Reflux;

upstream raw materials:

3,5-dibromobenzaldehyde

benzamidine monohydrochloride

acetophenone

4-chloro-2,6-diphenyl-1,3-pyrimidine

Downstream raw materials:

C₄₆H₃₀N₄