4-BROMO-1-[(4-METHYLPHENYL)SULFONYL]-1H-PYRROLO[2,3-B]PYRIDINE

Base Information

Chemical Name:4-BROMO-1-[(4-METHYLPHENYL)SULFONYL]-1H-PYRROLO[2,3-B]PYRIDINE
CAS No.:348640-07-3
Molecular Formula:C14H11BrN2O2S
Molecular Weight:351.224
Hs Code.:2933990090
Mol file:348640-07-3.mol

Synonyms:4-BROMO-1-[(4-METHYLPHENYL)SULFONYL]-1H-PYRROLO[2,3-B]PYRIDINE;1H-Pyrrolo[2,3-b]pyridine, 4-bromo-1-[(4-methylphenyl)sulfonyl]-;N-Tosyl-4-bromo-7-azaindole;4-Bormo-1-tosyl-7-azaindole;4-Bromo-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine;4-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine;4-Bromo-1-tosyl-7-azaindo...;4-BroMo-1-tosyl-7-azaindole

Suppliers and Price of 4-BROMO-1-[(4-METHYLPHENYL)SULFONYL]-1H-PYRROLO[2,3-B]PYRIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
4-Bromo-1-[(4-methylbenzene)sulfonyl]pyrrolo[2,3-b]pyridine
1 g
$ 180.00

SynQuest Laboratories
4-Bromo-1-[(4-methylbenzene)sulfonyl]pyrrolo[2,3-b]pyridine
5 g
$ 600.00

Matrix Scientific
4-Bromo-1-(p-tolylsulfonyl)pyrrolo[2,3-b]pyridine >95%
1g
$ 832.00

Matrix Scientific
4-Bromo-1-(p-tolylsulfonyl)pyrrolo[2,3-b]pyridine >95%
5g
$ 2126.00

Labseeker
4-BROMO-1-(TOLUENE-4-SULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE 95
10g
$ 2383.00

Crysdot
4-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine 96%
10g
$ 446.00

Crysdot
4-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine 96%
5g
$ 267.00

Crysdot
4-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine 96%
25g
$ 876.00

Chemenu
4-bromo-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine 95%+
25g
$ 1719.00

Chemenu
4-bromo-1-(4-methylbenzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine 95%+
250mg
$ 73.00

Total 42 raw suppliers

Chemical Property of 4-BROMO-1-[(4-METHYLPHENYL)SULFONYL]-1H-PYRROLO[2,3-B]PYRIDINE

Chemical Property:

Vapor Pressure:1.04E-10mmHg at 25°C
Refractive Index:1.684
Boiling Point:514.9 °C at 760 mmHg
PKA:2.14±0.30(Predicted)
Flash Point:265.2 °C
PSA：60.34000
Density:1.59 g/cm³
LogP:4.42500
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

4-Bromo-1-[(4-methylbenzene)sulfonyl]pyrrolo[2,3-b]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-BROMO-1-[(4-METHYLPHENYL)SULFONYL]-1H-PYRROLO[2,3-B]PYRIDINE

There total 6 articles about 4-BROMO-1-[(4-METHYLPHENYL)SULFONYL]-1H-PYRROLO[2,3-B]PYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 98-59-9
p-toluenesulfonyl chloride

: 348640-06-2
4-bromo-7-azaindole

: 348640-07-3
4-bromo-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: 4-bromo-7-azaindole; With tetrabutylammomium bromide; sodium hydride; In dichloromethane; at 0 ℃; for 0.25h; Inert atmosphere;

p-toluenesulfonyl chloride; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.0c00451

Reference yield: 76.0%

: 4-bromo-1H-pyrrolo[2,3-b]pyridine

: 98-59-9
p-toluenesulfonyl chloride

: 348640-07-3
4-bromo-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: 4-bromo-1H-pyrrolo[2,3-b]pyridine; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.166667h;

p-toluenesulfonyl chloride; In N,N-dimethyl-formamide; at 0 - 20 ℃;

Reference yield:

: 55052-24-9
1H-Pyrrolo[2,3-b]pyridine-7-oxide

: 348640-07-3
4-bromo-1-(toluene-4-sulfonyl)-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetramethylammonium bromide; Methanesulfonic anhydride / N,N-dimethyl-formamide / 24.5 h / 0 - 20 °C / Inert atmosphere

1.2: pH 7

2.1: sodium hydroxide / tetra(n-butyl)ammonium hydrogensulfate / dichloromethane / 1 h / 20 °C

With tetramethylammonium bromide; sodium hydroxide; Methanesulfonic anhydride; tetra(n-butyl)ammonium hydrogensulfate; In dichloromethane; N,N-dimethyl-formamide;