Diacetato[(S)-(-)-5,5'-bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole]ruthenium(II)

Base Information

• Chemical Name: Diacetato[(S)-(-)-5,5'-bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole]ruthenium(II)
• CAS No.: 373650-12-5
• Molecular Formula: C₄₂H₃₄O₈P₂Ru
• Molecular Weight: 829.745
• Mol file: 373650-12-5.mol

Synonyms:Diacetato[(S)-(-)-5,5-bis(diphenylphosphino)-4,4-bi-1,3-benzodioxole]ruthenium(II);(S)-Ru(OAc)2(SEGPHOS(R));Diacetato[(S)-(-)-5,5-bis(diphenylphosphino)-4,4-bi-1,3-benzodioxole]ruthenium(II) Ru(OAc)2[(S)-segphos];(S)-Ru(OAc)2(SEGPHOS)

Chemical Property of Diacetato[(S)-(-)-5,5'-bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole]ruthenium(II)

Chemical Property:

• Melting Point: >100°C
• PSA: 144.36000
• LogP: 3.83980
• Storage Temp.: 2-8°C
• Sensitive.: air sensitive

Purity/Quality:

98%,99%, ^*data from raw suppliers

Diacetato[(S)-(-)-5,5'-bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole]ruthenium(II) Ru(OAc)2[(S)-segphos(R)] ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: (S)-Ru(OAc)2(SEGPHOS?) can be used as a catalyst: To prepare highly chemo, enantio, and diastereoselective primary β-amino lactams by asymmetric reductive amination of racemic β-keto lactams. To synthesize chiral primary diarylmethylamines and sterically bulky benzylamines from diaryl and sterically hindered ketones via asymmetric reductive amination reaction. For the conversion of levulinic acid to optically active γ-valerolactone via asymmetric hydrogenation reaction.

Technology Process of Diacetato[(S)-(-)-5,5'-bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole]ruthenium(II)

There total 2 articles about Diacetato[(S)-(-)-5,5'-bis(diphenylphosphino)-4,4'-bi-1,3-benzodioxole]ruthenium(II) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

(S)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(diphenylphosphine) + [(η6-C6H6)RuCl2] (35796-48-6) + sodium acetate (127-09-3) → Ru[(S)-SegPhos](OAc)2 (373650-12-5,944450-48-0)

Guidance literature:

(S)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(diphenylphosphine); [(η6-C6H6)RuCl2]; In N,N-dimethyl-formamide; at 100 ℃; for 1.5h; Inert atmosphere; Schlenk technique;

sodium acetate; In methanol; N,N-dimethyl-formamide; for 0.333333h; Inert atmosphere; Schlenk technique;

DOI:10.1002/anie.201809719

Reference yield:

(S)-((4,4’-bi-1,3-benzodioxole)-5,5’-diyl)bis(diphenylphosphine) + [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 (52462-29-0) + sodium acetate (127-09-3) → Ru[(S)-SegPhos](OAc)2 (373650-12-5,944450-48-0)

Guidance literature:

(S)-(2H,2’H-[4,4’-bi-1,3-benzodioxole]-5,5’-diyl)bis(diphenylphosphane); [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; In methanol; toluene; at 50 ℃; for 1h;

sodium acetate; In methanol; toluene; at 50 ℃; for 2h;

upstream raw materials:

[ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂

sodium acetate

[(η6-C6H6)RuCl2]

Refernces

• 1、 -. "METHOD FOR PRODUCING A RUTHENIUM COMPLEX". Page/Page column 7. . Retrieved 2010/04/23.