3-Amino-6-chloropyrazine-2-carbonitrile

Base Information

Chemical Name:3-Amino-6-chloropyrazine-2-carbonitrile
CAS No.:17231-50-4
Molecular Formula:C5H3ClN4
Molecular Weight:154.559
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80575827
Wikidata:Q72434814
Mol file:17231-50-4.mol

Synonyms:17231-50-4;3-amino-6-chloro-2-pyrazinecarbonitrile;3-AMINO-6-CHLOROPYRAZINE-2-CARBONITRILE;MFCD10697784;DTXSID80575827;BCP23134;AKOS006283769;AB60487;BCP9000123;DS-0530;6-chloro-3-aminopyrazine-2-carbonitrile;SY104519;AM20070317;CS-0018966;A847706;Q-103300

Suppliers and Price of 3-Amino-6-chloropyrazine-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Amino-6-chloropyrazine-2-carbonitrile
100mg
$ 90.00

SynQuest Laboratories
3-Amino-6-chloropyrazine-2-carbonitrile 95%
1 g
$ 752.00

SynChem
3-Amino-6-chloropyrazine-2-carbonitrile 95%
5 g
$ 820.00

SynChem
3-Amino-6-chloropyrazine-2-carbonitrile 95%
1 g
$ 280.00

Matrix Scientific
3-Amino-6-chloro-2-pyrazinecarbonitrile 95+%
250mg
$ 300.00

Matrix Scientific
3-Amino-6-chloro-2-pyrazinecarbonitrile 95+%
1g
$ 425.00

Matrix Scientific
3-Amino-6-chloro-2-pyrazinecarbonitrile 95+%
5g
$ 1200.00

Crysdot
3-Amino-6-chloro-2-pyrazinecarbonitrile 95+%
5g
$ 743.00

Crysdot
3-Amino-6-chloro-2-pyrazinecarbonitrile 95+%
1g
$ 248.00

Chemenu
3-amino-6-chloropyrazine-2-carbonitrile 95%+
5g
$ 317.00

Total 37 raw suppliers

Chemical Property of 3-Amino-6-chloropyrazine-2-carbonitrile

Chemical Property:

Vapor Pressure:4.65E-05mmHg at 25°C
Melting Point:151-153℃
Refractive Index:1.621
Boiling Point:349.6 °C at 760 mmHg
PKA:-0.03±0.10(Predicted)
Flash Point:165.2 °C
PSA：75.59000
Density:1.53 g/cm³
LogP:1.16508
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:154.0046238
Heavy Atom Count:10
Complexity:162

Purity/Quality:

97% ^*data from raw suppliers

3-Amino-6-chloropyrazine-2-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(N=C(C(=N1)N)C#N)Cl

Technology Process of 3-Amino-6-chloropyrazine-2-carbonitrile

There total 3 articles about 3-Amino-6-chloropyrazine-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 773837-37-9
sodium cyanide

: 76537-18-3
3-bromo-5-chloro-2-aminopyrazine

: 17231-50-4
6-chloro-3-aminopyrazine-2-carbonitrile

Guidance literature:: With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In N,N-dimethyl-formamide; at 120 ℃; for 10h; Temperature; Inert atmosphere;
DOI:10.1007/s11696-018-0654-9

Reference yield:

: 1125-56-0
3-Amino-6-chlor-pyrazinamid

: 17231-50-4
6-chloro-3-aminopyrazine-2-carbonitrile

Guidance literature:: 3-amino-6-chloro-pyrazine-2-carboxylic acid amide; With N,N-dimethyl-formamide; trichlorophosphate; at 85 ℃;

With hydrogenchloride; water; Reflux;
DOI:10.1016/j.bmcl.2009.04.088