6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine

Base Information

Chemical Name:6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine
CAS No.:57744-68-0
Molecular Formula:C8H7ClO2
Molecular Weight:170.593
Hs Code.:2932999099
DSSTox Substance ID:DTXSID50442996
Nikkaji Number:J726.628F
Wikidata:Q82260650
Mol file:57744-68-0.mol

Synonyms:6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine;57744-68-0;6-chloro-2,3-dihydro-1,4-benzodioxine;6-Chloro-2,3-dihydro-1,4-benzodioxin;SCHEMBL3072209;DTXSID50442996;MFCD16622016;AKOS015900519;AS-40777;7-chloro-2,3-dihydro-[1,4]benzodioxine;CS-0248199;FT-0660686;EN300-39340;Q-103550;Z382713970

Suppliers and Price of 6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-Chloro-2,3-dihydro-1,4-benzodioxin
500mg
$ 145.00

SynQuest Laboratories
6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine 95%
5 g
$ 1064.00

SynQuest Laboratories
6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine 95%
1 g
$ 360.00

Crysdot
6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine 95+%
5g
$ 470.00

Chemenu
6-chloro-2,3-dihydrobenzo[b][1,4]dioxine 95%
5g
$ 445.00

Apolloscientific
6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine 95%
1g
$ 225.00

Apolloscientific
6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine 95%
5g
$ 665.00

American Custom Chemicals Corporation
6-CHLORO-2,3-DIHYDRO-1,4-BENZODIOXINE 95.00%
1G
$ 765.23

American Custom Chemicals Corporation
6-CHLORO-2,3-DIHYDRO-1,4-BENZODIOXINE 95.00%
5G
$ 1295.03

American Custom Chemicals Corporation
6-CHLORO-2,3-DIHYDRO-1,4-BENZODIOXINE 95.00%
2.5G
$ 1065.66

Total 19 raw suppliers

Chemical Property of 6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine

Chemical Property:

Vapor Pressure:0.053mmHg at 25°C
Refractive Index:1.557
Boiling Point:242.266°C at 760 mmHg
Flash Point:104.4°C
PSA：18.46000
Density:1.309g/cm³
LogP:2.11120
Storage Temp.:2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:170.0134572
Heavy Atom Count:11
Complexity:140

Purity/Quality:

97% ^*data from raw suppliers

6-Chloro-2,3-dihydro-1,4-benzodioxin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC2=C(O1)C=CC(=C2)Cl
Uses 6-Chloro-2,3-dihydro-1,4-benzodioxin can be used to prepare naphthylsulfonylamino hydroxamic acid as matrix metalloproteinase MMP-12 and MMP-13 inhibitors.

Technology Process of 6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine

There total 8 articles about 6-Chloro-2,3-dihydrobenzo[b][1,4]dioxine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 2138-22-9
4-chloro-1,2-benzenediol

: 106-93-4
ethylene dibromide

: 57744-68-0
6-chloro-2,3-dihydrobenzo[b][1,4]dioxine

Guidance literature:: With potassium carbonate; In ethylene glycol; at 130 ℃; for 48h; Inert atmosphere;

Reference yield: 23.0%

: 1892-43-9
2-(4-chlorophenoxy)ethanol

: 57744-68-0
6-chloro-2,3-dihydrobenzo[b][1,4]dioxine

Guidance literature:: With [bis(acetoxy)iodo]benzene; iodine; In 1,2-dichloro-ethane; at 60 - 70 ℃; Irradiation;
DOI:10.1016/0040-4039(96)00313-9

Reference yield: 15.0%

: 493-09-4
benzo-1,4-dioxane

: 57744-68-0
6-chloro-2,3-dihydrobenzo[b][1,4]dioxine

: 123972-41-8
6-(N,N-Dimethylamino)benzo-1,4-dioxane

: 67471-04-9
6,7-dichloro-2,3-dihydro-1,4-benzodioxin

Guidance literature:: With dimethylchloroamine; sulfuric acid; iron(II) sulfate; acetic acid; at 10 - 20 ℃; for 1h; Yield given;
DOI:10.1007/BF00472380