ethyl 6-bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylate

Base Information

Chemical Name:ethyl 6-bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylate
CAS No.:16052-67-8
Molecular Formula:C12H12BrNO3
Molecular Weight:298.13
Hs Code.:
DSSTox Substance ID:DTXSID20351440
Wikidata:Q27187496
ChEMBL ID:CHEMBL1450104
Mol file:16052-67-8.mol

Synonyms:ethyl 6-bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylate;16052-67-8;6-Bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylic acid ethyl ester;SMR000068905;Oprea1_081513;Oprea1_343666;CBDivE_000175;MLS000052948;SCHEMBL2959678;CHEMBL1450104;DTXSID20351440;CHEBI:108571;HMS2354O15;STK062390;AKOS000507260;FT-0723248;2-methyl-3-carbethoxy-5-hydroxy-6-bromoindole;AE-848/02136055;SR-01000525068;SR-01000525068-1;Q27187496

Suppliers and Price of ethyl 6-bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of ethyl 6-bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylate

Chemical Property:

Melting Point:198-199 °C(Solv: ethyl acetate (141-78-6))
Boiling Point:421.0±40.0 °C(Predicted)
PKA:7?+-.0.40(Predicted)
PSA：62.32000
Density:1.592±0.06 g/cm3(Predicted)
LogP:3.12110
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:297.00006
Heavy Atom Count:17
Complexity:300

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(NC2=CC(=C(C=C21)O)Br)C

Technology Process of ethyl 6-bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylate

There total 4 articles about ethyl 6-bromo-5-hydroxy-2-methyl-1H-indole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%