(18-Hydroxy-7,11-dimethyl-6-oxo-14-pentacyclo[8.8.0.02,7.03,5.011,16]octadec-16-enyl) 2,2-dimethylpropanoate

Base Information

Chemical Name:(18-Hydroxy-7,11-dimethyl-6-oxo-14-pentacyclo[8.8.0.02,7.03,5.011,16]octadec-16-enyl) 2,2-dimethylpropanoate
CAS No.:82543-09-7
Molecular Formula:C25H36 O4
Molecular Weight:400.558
Hs Code.:
European Community (EC) Number:617-344-8
Mol file:82543-09-7.mol

Synonyms:(18-Hydroxy-7,11-dimethyl-6-oxo-14-pentacyclo[8.8.0.02,7.03,5.011,16]octadec-16-enyl) 2,2-dimethylpropanoate;82543-09-7;FT-0669786

Suppliers and Price of (18-Hydroxy-7,11-dimethyl-6-oxo-14-pentacyclo[8.8.0.02,7.03,5.011,16]octadec-16-enyl) 2,2-dimethylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7β-Hydroxy-15β,16β-methylene-3β-pivaloyloxy-5-androsten-17-one
250mg
$ 1100.00

Chemenu
DrospirenoneIntermediates 95%
1g
$ 729.00

American Custom Chemicals Corporation
7-BETA-HYDROXY-15-BETA,16-BETA-METHYLENE-3BETA-PIVALOYLOXY ANDROST-5-EN-17-ONE 95.00%
5MG
$ 505.58

Total 47 raw suppliers

Chemical Property of (18-Hydroxy-7,11-dimethyl-6-oxo-14-pentacyclo[8.8.0.02,7.03,5.011,16]octadec-16-enyl) 2,2-dimethylpropanoate

Chemical Property:

Boiling Point:515.5±50.0 °C(Predicted)
PKA:13.95±0.70(Predicted)
PSA：63.60000
Density:1.17±0.1 g/cm3(Predicted)
LogP:4.30290
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:400.26135963
Heavy Atom Count:29
Complexity:791

Purity/Quality:

99.9% ^*data from raw suppliers

7β-Hydroxy-15β,16β-methylene-3β-pivaloyloxy-5-androsten-17-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC12CCC(CC1=CC(C3C2CCC4(C3C5CC5C4=O)C)O)OC(=O)C(C)(C)C
Uses Drospirenone intermediate.

Technology Process of (18-Hydroxy-7,11-dimethyl-6-oxo-14-pentacyclo[8.8.0.02,7.03,5.011,16]octadec-16-enyl) 2,2-dimethylpropanoate

There total 7 articles about (18-Hydroxy-7,11-dimethyl-6-oxo-14-pentacyclo[8.8.0.02,7.03,5.011,16]octadec-16-enyl) 2,2-dimethylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1774-47-6
trimethylsulfoxonium iodide

: 85390-94-9
7β-hydroxy-3β,15α-dipivaloyloxy-5-androsten-17-one

: 82543-09-7
7β-hydroxy-15β,16β-methylene-3β-pivaloyloxy-5-androsten-17-one

Guidance literature:: With sodium hydroxide; In dimethyl sulfoxide; for 1h; Ambient temperature;

Reference yield: 65.0%

: 1538-75-6
2,2-dimethylpropanoic anhydride

: 82543-07-5
3β,7β-dihydroxy-15β,16β-methylene-5-androsten-17-one

: 82543-09-7
7β-hydroxy-15β,16β-methylene-3β-pivaloyloxy-5-androsten-17-one

Guidance literature:: With dmap; In pyridine; for 72h; Ambient temperature;

Reference yield:

: 53-43-0
dehydroepiandrosterone

: 82543-09-7
7β-hydroxy-15β,16β-methylene-3β-pivaloyloxy-5-androsten-17-one

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / Colletotrichum lini / 36 h

2: 97 percent / 35 percent HClO₄ / various solvent(s) / 4 h / Ambient temperature

3: 90 percent / 4-dimethylaminopyridine / pyridine / 4 h / 50 °C

4: 91 percent / NaOH / dimethylsulfoxide / 1 h / Ambient temperature

With dmap; sodium hydroxide; perchloric acid; Colletotrichum lini; In pyridine; dimethyl sulfoxide;