Technology Process of 3H-Cycloprop[15,16]androsta-5,15-dien-17-one,15,16-dihydro-3,7-dihydroxy-,
There total 1 articles about 3H-Cycloprop[15,16]androsta-5,15-dien-17-one,15,16-dihydro-3,7-dihydroxy-, which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
Botryodiplodia malorum;
for 40h;
- Guidance literature:
-
With
dmap;
In
pyridine;
for 72h;
Ambient temperature;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 65 percent / dimethylaminopyridine / pyridine / 72 h / Ambient temperature
2: 98 percent / tert-butylhydroperoxide, VO(C5H7O2)2 / toluene / 2 h / 80 °C
3: 79 percent / P(C6H5)3 / CCl4; CH2Cl2; pyridine / 2 h / 0 deg C to room temp.
4: 75 percent / Zn / acetic anhydride; tetrahydrofuran / 1.5 h / 70 °C
5: 94 percent / KOH, NaClO4 / tetrahydrofuran; methanol / 2.5 h / Ambient temperature
6: 88 percent / Zn/Cu / 1,2-dimethoxy-ethane / 5 h / 55 °C
7: 69 percent / KOEt / tetrahydrofuran / 2 h / Ambient temperature
With
tert.-butylhydroperoxide; dmap; potassium hydroxide; VO(C5H7O2)2; potassium ethoxide; sodium perchlorate; copper; triphenylphosphine; zinc;
In
tetrahydrofuran; pyridine; methanol; tetrachloromethane; 1,2-dimethoxyethane; dichloromethane; acetic anhydride; toluene;