7-BROMO-2,3-DIHYDRO-1-BENZOFURAN

Base Information

• Chemical Name: 7-BROMO-2,3-DIHYDRO-1-BENZOFURAN
• CAS No.: 206347-30-0
• Molecular Formula: C8H7BrO
• Molecular Weight: 199.047
• Hs Code.: 2932999099
• Mol file: 206347-30-0.mol

Synonyms:7-BROMO-2,3-DIHYDRO-1-BENZOFURAN;7-Bromo-2,3-dihydrobenzofuran;7-Bromo-2,3-dihydrobenzo[b]furan

Chemical Property of 7-BROMO-2,3-DIHYDRO-1-BENZOFURAN

Chemical Property:

• Vapor Pressure: 0.028mmHg at 25°C
• Boiling Point: 254.359°C at 760 mmHg
• Flash Point: 100.745°C
• PSA: 9.23000
• Density: 1.583g/cm³
• LogP: 2.38400
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C

Purity/Quality:

98%min ^*data from raw suppliers

7-Bromo-2,3-dihydrobenzofuran ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-BROMO-2,3-DIHYDRO-1-BENZOFURAN

There total 1 articles about 7-BROMO-2,3-DIHYDRO-1-BENZOFURAN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,3-dibromo-2-(2-bromoethoxy)benzene (206347-32-2) → 2.3-dihydrobenzofuran (496-16-2) + 7-bromo-2,3-dihydrobenzofuran (206347-30-0)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 0 ℃; Cooling with ethanol-dry ice;

Reference yield: 64.0%

bis(pinacol)diborane (73183-34-3) + 7-bromo-2,3-dihydrobenzofuran (206347-30-0) → 7-( 4,4,5,5-tetra methyl-[1,3,2]dioxaborola n-2-yl)-2,3-dihydro-benzofuran (934586-50-2)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In toluene; Reflux;

Reference yield:

toluene-4-sulfonic acid (104-15-4) + 7-bromo-2,3-dihydrobenzofuran (206347-30-0) → 7-bromo-5-[(4-methylphenyl)sulfonyl]-2,3-dihydro-1-benzofuran (856679-83-9)

Guidance literature:

With methanesulfonic acid; phosphorus pentoxide; at 20 ℃;

upstream raw materials:

1,3-dibromo-2-(2-bromoethoxy)benzene

Downstream raw materials:

7-bromo-5-[(4-methylphenyl)sulfonyl]-2,3-dihydro-1-benzofuran

2,3-dihydrobenzofuran-7-sulfonyl chloride

7-( 4,4,5,5-tetra methyl-[1,3,2]dioxaborola n-2-yl)-2,3-dihydro-benzofuran

Refernces