dimethyl 5-(propionylamino)isophthalate

Base Information

• Chemical Name: dimethyl 5-(propionylamino)isophthalate
• CAS No.: 198284-02-5
• Molecular Formula: C₁₃H₁₅NO₅
• Molecular Weight: 265.266
• Mol file: 198284-02-5.mol

Synonyms:

Chemical Property of dimethyl 5-(propionylamino)isophthalate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of dimethyl 5-(propionylamino)isophthalate

There total 1 articles about dimethyl 5-(propionylamino)isophthalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl 5-aminoisophthalate (99-27-4) + propionyl chloride (79-03-8) → C13H15NO5 (198284-02-5)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1039/c4nj02371d

Reference yield: 62.0%

C13H15NO5 (198284-02-5) → 5-N-propionylaminoisophtalic acid

Guidance literature:

With sodium hydroxide; In methanol; water; at 80 ℃; for 4h;

DOI:10.1039/c4nj02371d

Reference yield:

C13H15NO5 (198284-02-5) → C11H15NO8Zn*H2O

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydroxide / methanol; water / 4 h / 80 °C

2.1: methanol; N,N-dimethyl-formamide / 0.5 h / 20 °C

2.2: 48 h / 75 °C / Sealed tube

With sodium hydroxide; In methanol; water; N,N-dimethyl-formamide;

DOI:10.1039/c4nj02371d

upstream raw materials:

dimethyl 5-aminoisophthalate

propionyl chloride

Refernces