C₂₂H₂₅N₃O₄

Base Information

• Chemical Name: C₂₂H₂₅N₃O₄
• CAS No.: 1224437-09-5
• Molecular Formula: C₂₂H₂₅N₃O₄
• Molecular Weight: 395.458
• Mol file: 1224437-09-5.mol

Synonyms:

Chemical Property of C₂₂H₂₅N₃O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₅N₃O₄

There total 1 articles about C₂₂H₂₅N₃O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-Aminophenyl)-(pyridin-4-yl)methanone (91973-39-6) + 1-(tert-butoxycarbonyl)-L-proline (15761-39-4,59433-50-0) → C22H25N3O4 (1224437-09-5)

Guidance literature:

1-(tert-butoxycarbonyl)-L-proline; With triethylamine; isobutyl chloroformate; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

(2-Aminophenyl)-(pyridin-4-yl)methanone; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2010.01.109

Reference yield:

C22H25N3O4 (1224437-09-5) → C17H17N3O2 (1224437-13-1)

Guidance literature:

C₂₂H₂₅N₃O₄; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.5h;

With sodium hydroxide; In dichloromethane; water; pH=9 - 11;

DOI:10.1016/j.tet.2010.01.109

Reference yield:

C22H25N3O4 (1224437-09-5) + methyl iodide (74-88-4) → C23H27N3O4 (1224437-20-0)

Guidance literature:

C₂₂H₂₅N₃O₄; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.166667h; Inert atmosphere;

methyl iodide; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2010.01.109

upstream raw materials:

(2-Aminophenyl)-(pyridin-4-yl)methanone

1-(tert-butoxycarbonyl)-L-proline

Downstream raw materials:

C₁₇H₁₇N₃O₂

C₂₃H₂₇N₃O₄