2-Amino-6-chloronicotinaldehyde

Base Information

• Chemical Name: 2-Amino-6-chloronicotinaldehyde
• CAS No.: 58584-61-5
• Molecular Formula: C₆H₅ClN₂O
• Molecular Weight: 156.572
• Hs Code.: 2933399090
• European Community (EC) Number: 849-083-2
• DSSTox Substance ID: DTXSID50482832
• Wikidata: Q72434859
• Mol file: 58584-61-5.mol

Synonyms:2-Amino-6-chloronicotinaldehyde;58584-61-5;2-amino-6-chloropyridine-3-carbaldehyde;2-AMINO-6-CHLORO-3-PYRIDINECARBOXALDEHYDE;MFCD13190075;2-AMINO-6-CHLORO-PYRIDINE-3-CARBALDEHYDE;SCHEMBL10117554;DTXSID50482832;IOLHHGBKOCKPCY-UHFFFAOYSA-N;AKOS016011798;AB69707;SY143057;2-amino-6-chloropyridine-3-carboxaldehyde;CS-0088194;EN300-112513;A869402;Z1255444024

Chemical Property of 2-Amino-6-chloronicotinaldehyde

Chemical Property:

• PSA: 55.98000
• Density: 1.442
• LogP: 1.71090
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 156.0090405
• Heavy Atom Count: 10
• Complexity: 131

Purity/Quality:

97% ^*data from raw suppliers

2-Amino-6-chloronicotinaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NC(=C1C=O)N)Cl
• Uses: 2-Amino-6-chloronicotinaldehyde is a useful synthetic compound.

Technology Process of 2-Amino-6-chloronicotinaldehyde

There total 9 articles about 2-Amino-6-chloronicotinaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

→ 2-amino-6-chloropyridine-3-carbaldehyde (58584-61-5)

Guidance literature:

Reference yield: 94.0%

tert-butyl N-(6-chloro-3-formyl-2-pyridyl)carbamate (294659-72-6) → 2-amino-6-chloropyridine-3-carbaldehyde (58584-61-5)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃;

Reference yield: 93.0%

(2-amino-6-chloro-pyridin-3-yl)-methanol (58584-60-4) → 2-amino-6-chloropyridine-3-carbaldehyde (58584-61-5)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; for 63h; Sonication;

upstream raw materials:

t-butyl N-(6-chloro-2-pyridinyl)carbamate

6-chloropyridin-2-amine

tert-butyl N-(6-chloro-3-formyl-2-pyridyl)carbamate

2,6-dichloropyridine-3-carboxylic acid