(2-Amino-6-chloropyridin-3-yl)methanol

Base Information

• Chemical Name: (2-Amino-6-chloropyridin-3-yl)methanol
• CAS No.: 58584-60-4
• Molecular Formula: C₆H₇ClN₂O
• Molecular Weight: 158.587
• DSSTox Substance ID: DTXSID90482831
• Wikidata: Q82319646

Synonyms:(2-Amino-6-chloropyridin-3-yl)methanol;58584-60-4;SCHEMBL18304948;DTXSID90482831;AKOS006306520;SB54660;CS-0087881;F95745

Chemical Property of (2-Amino-6-chloropyridin-3-yl)methanol

Chemical Property:

• XLogP3: 1.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 158.0246905
• Heavy Atom Count: 10
• Complexity: 112

Purity/Quality:

95% purity ^*data from raw suppliers

(2-Amino-6-chloropyridin-3-yl)methanol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=NC(=C1CO)N)Cl

Technology Process of (2-Amino-6-chloropyridin-3-yl)methanol

There total 7 articles about (2-Amino-6-chloropyridin-3-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-amino-6-chloronicotinic acid (58584-92-2) → (2-amino-6-chloro-pyridin-3-yl)-methanol (58584-60-4)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 20.5h; Reagent/catalyst; Inert atmosphere;

Reference yield: 45.0%

2-amino-6-chloro-N-methoxy-N-methylnicotinamide (873936-99-3) → (2-amino-6-chloro-pyridin-3-yl)-methanol (58584-60-4)

Guidance literature:

With diisobutylaluminium hydride; In tetrahydrofuran; toluene; at 0 ℃;

Reference yield:

2,6-dichloro-3-(hydroxymethyl)pyridine (55304-90-0) → (2-amino-6-chloro-pyridin-3-yl)-methanol (58584-60-4)

Guidance literature:

With ammonia; copper; In ethanol; at 120 ℃; for 6h;

DOI:10.1016/j.bmcl.2006.04.009

upstream raw materials:

2,6-dichloro-3-(hydroxymethyl)pyridine

2,6-dichloropyridine

2,6-dichloro-pyridine-3-carbaldehyde

2-amino-6-chloronicotinic acid

Downstream raw materials:

2-amino-6-chloropyridine-3-carbaldehyde

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 58584-60-4 (2-amino-6-chloro-pyridin-3-yl)-methanol

Send

Send

Metric Ton KG G Pound L ML

Send

Send