3,5-Dimethylpyridine-4-boronic acid pinacol ester

Base Information

Chemical Name:3,5-Dimethylpyridine-4-boronic acid pinacol ester
CAS No.:1032358-02-3
Molecular Formula:C₁₃H₂₀BNO₂
Molecular Weight:233.118
Hs Code.:2934999090
Mol file:1032358-02-3.mol

Synonyms:(3,5-Dimethyl-4-pyridyl)-(2-hydroxy-1,1,2-trimethyl-propoxy)borinic acid;

Suppliers and Price of 3,5-Dimethylpyridine-4-boronic acid pinacol ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3,5-DIMETHYL PYRIDINE-4-BORONIC ACID PINACOL ESTER 95.00%
1G
$ 1819.13

American Custom Chemicals Corporation
3,5-DIMETHYL PYRIDINE-4-BORONIC ACID PINACOL ESTER 95.00%
500MG
$ 963.90

Alichem
3,5-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
1g
$ 821.76

Alfa Aesar
3,5-Dimethylpyridine-4-boronic acid pinacol ester, 95%
500mg
$ 853.00

Total 14 raw suppliers

Chemical Property of 3,5-Dimethylpyridine-4-boronic acid pinacol ester

Chemical Property:

Boiling Point:386.952 °C at 760 mmHg
PKA:5.00±0.30(Predicted)
Flash Point:187.822 °C
PSA：31.35000
Density:1.058 g/cm³
LogP:1.99760
Storage Temp.:2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

3,5-DIMETHYL PYRIDINE-4-BORONIC ACID PINACOL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3,5-Dimethylpyridine-4-boronic acid pinacol ester

There total 3 articles about 3,5-Dimethylpyridine-4-boronic acid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 201286-65-9
4-bromo-3,5-dimethylpyridine

: 73183-34-3
bis(pinacol)diborane

: 1032358-02-3
3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2yl)-pyridine

Guidance literature:: With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; dichloro bis(acetonitrile) palladium(II); potassium acetate; In 1,4-dioxane; at 95 ℃; for 16h;

Reference yield:

: 76-09-5
2,3-dimethyl-2,3-butane diol

: C₇H₁₀BNO₂

: 1032358-02-3
3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2yl)-pyridine

Guidance literature:: With magnesium sulfate; In toluene; for 2h; Reflux;
DOI:10.1016/j.tet.2011.10.115

Reference yield:

: 1120-87-2
4-bromopyridin

: 1032358-02-3
3,5-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2yl)-pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / diethyl ether; cyclohexane / 0.25 h / -78 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

1.3: Inert atmosphere

2.1: magnesium sulfate / toluene / 2 h / Reflux

With n-butyllithium; magnesium sulfate; In diethyl ether; cyclohexane; toluene;
DOI:10.1016/j.tet.2011.10.115