4-Phenylquinoline

Base Information

• Chemical Name: 4-Phenylquinoline
• CAS No.: 605-03-8
• Molecular Formula: C15H11N
• Molecular Weight: 205.259
• Hs Code.: 2933499090
• DSSTox Substance ID: DTXSID90334785
• Nikkaji Number: J134.377G
• Wikidata: Q72498716
• Mol file: 605-03-8.mol

Synonyms:4-phenylquinoline;605-03-8;Quinoline, 4-phenyl-;4-phenyl-quinoline;SCHEMBL35327;DTXSID90334785;AMY10508;MFCD13689220;AKOS015998658;SB71718;DS-18130;CS-0156410;FT-0713454;L10115

Chemical Property of 4-Phenylquinoline

Chemical Property:

• Vapor Pressure: 7.39E-05mmHg at 25°C
• Melting Point: 61-62℃
• Refractive Index: 1.6550 (estimate)
• Boiling Point: 353℃
• PKA: 5.16±0.13(Predicted)
• Flash Point: 154℃
• PSA: 12.89000
• Density: 1.127
• LogP: 3.90180
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 205.089149355
• Heavy Atom Count: 16
• Complexity: 220

Purity/Quality:

97% ^*data from raw suppliers

4-Phenylquinoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=NC3=CC=CC=C23

Technology Process of 4-Phenylquinoline

There total 113 articles about 4-Phenylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-chloroquinoline (611-35-8) + phenylboronic acid (98-80-6) → 4-phenylquinoline (605-03-8)

Guidance literature:

With dihydrogen dichloro-bis(di-tert-butylphosphinito-κP)palladium(2-); caesium carbonate; In 1,4-dioxane; at 100 ℃; for 20h;

DOI:10.1002/ejoc.200500843

Reference yield: 97.0%

4-phenyl-1,2,3,4-tetrahydroquinoline (30290-78-9) → 4-phenylquinoline (605-03-8)

Guidance literature:

With 4-methoxypyridine; copper(l) iodide; di-isopropyl azodicarboxylate; oxygen; In acetonitrile; at 20 ℃; for 15h; Reagent/catalyst;

DOI:10.1021/acs.orglett.6b03166

Reference yield: 95.0%

(Z)-β-bromo-(2'-nitrophenyl)cinnamaldehyde → 4-phenylquinoline (605-03-8)

Guidance literature:

With hydrogen; nickel; In ethanol; for 1.5h;

DOI:10.1016/j.tetlet.2007.03.078

upstream raw materials:

quinoline

dibenzoyl peroxide

4-phenyl-[3]quinolylamine

1-ethyl-4-phenyl-decahydro-quinoline

Downstream raw materials:

4-(3-nitro-phenyl)-quinoline

1-methyl-4-phenyl-1,2,3,4-tetrahydroquinoline

phenyl(4-phenyl-3,4-dihydroquinolin-1(2H)-yl)methanone

C₁₅H₁₇ClN₃Pt⁽¹⁺⁾*Cl^(1-)