Technology Process of (1S,2R,3R,5R,8R,10S)-2-benzyloxy-5-phenyl-4,6,11-trioxatricyclo<8.1.03.8>undecane
There total 5 articles about (1S,2R,3R,5R,8R,10S)-2-benzyloxy-5-phenyl-4,6,11-trioxatricyclo<8.1.03.8>undecane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: p-TsOH / dimethylformamide / 2 h / 60 °C
2: aq. sodium phosphoric acid, sodium phosphinic acid, m-chloroperoxybenzoic acid / CH2Cl2 / 2 h / Ambient temperature
3: 1) NaH / 1) DMF, r.t., 1 h, 2) DMF, 1 h
With
sodium hypophosphite; sodium hydride; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; sodium phosphate;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0008-6215(00)90491-9
- Guidance literature:
-
Multi-step reaction with 4 steps
1: LiAlH4 / tetrahydrofuran / 2 h / Ambient temperature
2: p-TsOH / dimethylformamide / 2 h / 60 °C
3: aq. sodium phosphoric acid, sodium phosphinic acid, m-chloroperoxybenzoic acid / CH2Cl2 / 2 h / Ambient temperature
4: 1) NaH / 1) DMF, r.t., 1 h, 2) DMF, 1 h
With
lithium aluminium tetrahydride; sodium hypophosphite; sodium hydride; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; sodium phosphate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0008-6215(00)90491-9
- Guidance literature:
-
Multi-step reaction with 3 steps
1: p-TsOH / dimethylformamide / 2 h / 60 °C
2: aq. sodium phosphoric acid, sodium phosphinic acid, m-chloroperoxybenzoic acid / CH2Cl2 / 2 h / Ambient temperature
3: 1) NaH / 1) DMF, r.t., 1 h, 2) DMF, 1 h
With
sodium hypophosphite; sodium hydride; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; sodium phosphate;
In
dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0008-6215(00)90491-9
