3-Bromotetrahydrofuran

Base Information

• Chemical Name: 3-Bromotetrahydrofuran
• CAS No.: 19311-37-6
• Molecular Formula: C4H7BrO
• Molecular Weight: 151.003
• Hs Code.: 2932190090
• European Community (EC) Number: 829-504-6
• DSSTox Substance ID: DTXSID50513211
• Nikkaji Number: J708.932E
• Mol file: 19311-37-6.mol

Synonyms:3-BROMOTETRAHYDROFURAN;19311-37-6;3-bromooxolane;MFCD09056777;FURAN, 3-BROMOTETRAHYDRO-;3-bromanyloxolane;SCHEMBL264306;DTXSID50513211;NPZIPXHYLXTEAB-UHFFFAOYSA-N;BCP20925;AKOS012637885;CS-W004035;PB20333;3-bromooxolane pound>>3-bromanyloxolane;AS-30699;SY013735;AM20090126;FT-0684784;EN300-111527;A813627;J-512142

Chemical Property of 3-Bromotetrahydrofuran

Chemical Property:

• Vapor Pressure: 4.07mmHg at 25°C
• Refractive Index: 1.503
• Boiling Point: 559.3 °C at 760 mmHg
• Flash Point: 292 °C
• PSA: 9.23000
• Density: 1.558g/cm³
• LogP: 1.17020
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 149.96803
• Heavy Atom Count: 6
• Complexity: 46.8

Purity/Quality:

98%, ^*data from raw suppliers

3-Bromotetrahydrofuran ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COCC1Br

Technology Process of 3-Bromotetrahydrofuran

There total 6 articles about 3-Bromotetrahydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

homoalylic alcohol (627-27-0) → (RS)-3-bromotetrahydrofuran (19311-37-6)

Guidance literature:

With ammonium cerium (IV) nitrate; dihydrogen peroxide; lithium bromide; In water; at 65 - 70 ℃; for 15h;

DOI:10.1007/s11172-012-0064-z

Reference yield: 92.0%

2,3-dibromotetrahydrofuran (52911-58-7) → (RS)-3-bromotetrahydrofuran (19311-37-6)

Guidance literature:

With sodium tetrahydroborate; In diethylene glycol dimethyl ether; at 40 - 50 ℃; for 5h;

Reference yield: 70.0%

3-Hydroxytetrahydrofuran (453-20-3,84921-89-1,864447-89-2) → (RS)-3-bromotetrahydrofuran (19311-37-6)

Guidance literature:

With 1-bromo-N,N,2-trimethyl-1-propen-1-amine; methyloxirane; In dichloromethane; 1.) -78 deg C to r.t., 2.) r.t., overnight;

DOI:10.1039/a701999h

upstream raw materials:

3,4-Dibromobutan-1-ol

3-Hydroxytetrahydrofuran

homoalylic alcohol

diethyl ether

Downstream raw materials:

homoalylic alcohol

thiophene

thiophene

(E/Z)-2-buten-1-ol