3-(4-Methoxyphenyl)-4-methylisothiazol-5-amine

Base Information

Chemical Name:3-(4-Methoxyphenyl)-4-methylisothiazol-5-amine
CAS No.:1050392-29-4
Molecular Formula:C11H12N2OS
Molecular Weight:220.295
Hs Code.:2934999090
DSSTox Substance ID:DTXSID90694790
Nikkaji Number:J3.475.423C
Wikidata:Q72517755
Mol file:1050392-29-4.mol

Synonyms:3-(4-Methoxyphenyl)-4-methylisothiazol-5-amine;1050392-29-4;3-(4-methoxyphenyl)-4-methyl-1,2-thiazol-5-amine;3-(4-methoxy-phenyl)-4-methylisothiazol-5-ylamine;SCHEMBL1838245;DTXSID90694790;VAIJKTHAHKDKKB-UHFFFAOYSA-N;AMY20218;FT-0756525;3-(4-methoxyphenyl)-4-methylisothiazol-5-ylamine;3-(4-Methoxyphenyl)-4-methylisothiazole-5-amine;A801141;3-(4-METHOXYPHENYL)-4-METHYL-5-ISOTHIAZOLAMINE;3-(4-methoxyphenyl)-4-methyl-isothiazol-5-amine

Suppliers and Price of 3-(4-Methoxyphenyl)-4-methylisothiazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-(4-Methoxyphenyl)-4-methylisothiazol-5-amine 95+%
1g
$ 772.00

Chemenu
3-(4-methoxyphenyl)-4-methylisothiazol-5-amine 95%
1g
$ 729.00

American Custom Chemicals Corporation
3-(4-METHOXYPHENYL)-4-METHYLISOTHIAZOL-5-AMINE 95.00%
5MG
$ 497.75

Alichem
3-(4-Methoxyphenyl)-4-methylisothiazol-5-amine
1g
$ 653.12

Total 10 raw suppliers

Chemical Property of 3-(4-Methoxyphenyl)-4-methylisothiazol-5-amine

Chemical Property:

Boiling Point:294.6 °C at 760 mmHg
Flash Point:132 °C
PSA：76.38000
Density:1.223g/cm³
LogP:3.29050
Storage Temp.:2-8°C
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:220.06703418
Heavy Atom Count:15
Complexity:207

Purity/Quality:

97% ^*data from raw suppliers

3-(4-Methoxyphenyl)-4-methylisothiazol-5-amine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(SN=C1C2=CC=C(C=C2)OC)N

Technology Process of 3-(4-Methoxyphenyl)-4-methylisothiazol-5-amine

There total 5 articles about 3-(4-Methoxyphenyl)-4-methylisothiazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.2%

: (Z)-3-amino-3-(4-methoxyphenyl)-2-methyl-thioacrylamide

: 1050392-29-4
3-(4-methoxy-phenyl)-4-methylisothiazol-5-ylamine

Guidance literature:: With dihydrogen peroxide; In methanol; water; for 3h;

Reference yield:

: 1050392-22-7
C₁₁H₁₄N₂OS

: 1050392-29-4
3-(4-methoxy-phenyl)-4-methylisothiazol-5-ylamine

Guidance literature:: With dihydrogen peroxide; In methanol; at 20 ℃;
DOI:10.1016/j.bmcl.2012.02.003

Reference yield:

: 874-90-8
4-methoxybenzonitrile

: 1050392-29-4
3-(4-methoxy-phenyl)-4-methylisothiazol-5-ylamine

Guidance literature:: Multi-step reaction with 3 steps

1: sodium t-butanolate / tetrahydrofuran / 20 °C

2: hydrogenchloride / 1,4-dioxane / 20 °C

3: dihydrogen peroxide / methanol / 20 °C

With hydrogenchloride; dihydrogen peroxide; sodium t-butanolate; In tetrahydrofuran; 1,4-dioxane; methanol;
DOI:10.1016/j.bmcl.2012.02.003