Betamethasone 17-butyrate

Base Information

Chemical Name:Betamethasone 17-butyrate
CAS No.:5534-14-5
Molecular Formula:C₂₆H₃₅FO₆
Molecular Weight:462.559
Hs Code.:
DSSTox Substance ID:DTXSID30859705
Nikkaji Number:J350.613D

Synonyms:Betamethasone 17-butyrate;5534-14-5;(8S,9R,10S,11S,13S,14S,16S,17R)-9-Fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl butyrate;[(8S,9R,10S,11S,13S,14S,16S,17R)-9-Fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate;SCHEMBL1943651;DTXSID30859705

Suppliers and Price of Betamethasone 17-butyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Betamethasone17-Butyrate
1g
$ 1210.00

Medical Isotopes, Inc.
Betamethasone17-Butyrate
100 mg
$ 625.00

Total 8 raw suppliers

Chemical Property of Betamethasone 17-butyrate

Chemical Property:

Melting Point:195 °C
Boiling Point:589.2±50.0 °C(Predicted)
PKA:12.90±0.70(Predicted)
Density:1.26±0.1 g/cm3(Predicted)
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly, Sonicated)
XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:462.24176699
Heavy Atom Count:33
Complexity:941

Purity/Quality:

99% ^*data from raw suppliers

Betamethasone17-Butyrate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CO
Isomeric SMILES:CCCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CO
Uses Betamethasone 17-Butyrate is an impurity of Clobetasone 17-Butyrate (C583550), an glucocorticoid used for anti-inflammatory purposes.

Technology Process of Betamethasone 17-butyrate

There total 5 articles about Betamethasone 17-butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 43083-12-1
1,1,1-trimethoxybutane

: 378-44-9
betamethasone

: 5534-14-5
9α-fluoro-11β,17α,21-trihydroxy-16β-methyl-1,4-pregnadiene-3,20-dione 17-butyrate

Guidance literature:: With toluene-4-sulfonic acid; In N,N-dimethyl-formamide; benzene; for 1.25h; Ambient temperature;
DOI:10.1248/cpb.37.3286