tert-Butyl 4-(((6-methoxy-4-oxo-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-7-yl)oxy)methyl)piperidine-1-carboxylate

Base Information

Chemical Name:tert-Butyl 4-(((6-methoxy-4-oxo-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-7-yl)oxy)methyl)piperidine-1-carboxylate
CAS No.:264208-86-8
Molecular Formula:C26H37N3O7
Molecular Weight:503.59
Hs Code.:
DSSTox Substance ID:DTXSID70471283
Wikidata:Q82299762
Mol file:264208-86-8.mol

Synonyms:264208-86-8;tert-Butyl 4-(((6-methoxy-4-oxo-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-7-yl)oxy)methyl)piperidine-1-carboxylate;tert-butyl 4-[[3-(2,2-dimethylpropanoyloxymethyl)-6-methoxy-4-oxoquinazolin-7-yl]oxymethyl]piperidine-1-carboxylate;tert-Butyl 4-{[(3-{[(2,2-dimethylpropanoyl)oxy]methyl}-6-methoxy-4-oxo-3,4-dihydroquinazolin-7-yl)oxy]methyl}piperidine-1-carboxylate;SCHEMBL1614040;DTXSID70471283;NUSFDTVAVPUXCV-UHFFFAOYSA-N;6-methoxy-3-((pivaloyloxy)methyl)-7-((1-tert-butyloxycarbonylpiperidin-4-yl)methoxy)-3,4-dihydroquinazolin-4-one;7-(1(tert-butoxycarbonyl)piperidin-4-ylmethoxy)-6-methoxy-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-4-one;7-(1-(tert-butoxycarbonyl)piperidin-4-ylmethoxy) 6-methoxy-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-4-one;7-(1-(tert-butoxycarbonyl)piperidin-4-ylmethoxy)-6-methoxy-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-4-one;7-(N-tert-Butoxycarbonylpiperidin-4-ylmethoxy)-6-methoxy-3-pivaloyloxymethyl-3,4-dihydroquinazolin-4-one;tert-butyl 4-[[3-(2, 2-dimethylpropanoyloxymethyl)-6-methoxy-4-oxoquinazolin-7-yl]oxymethyl]piperidine-1-carboxylate

Suppliers and Price of tert-Butyl 4-(((6-methoxy-4-oxo-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-7-yl)oxy)methyl)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of tert-Butyl 4-(((6-methoxy-4-oxo-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-7-yl)oxy)methyl)piperidine-1-carboxylate

Chemical Property:

PSA：109.19000
LogP:3.91570
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:10
Exact Mass:503.26315053
Heavy Atom Count:36
Complexity:824

Purity/Quality:: 95%-98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C(=O)OCN1C=NC2=CC(=C(C=C2C1=O)OC)OCC3CCN(CC3)C(=O)OC(C)(C)C

Technology Process of tert-Butyl 4-(((6-methoxy-4-oxo-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-7-yl)oxy)methyl)piperidine-1-carboxylate

There total 3 articles about tert-Butyl 4-(((6-methoxy-4-oxo-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-7-yl)oxy)methyl)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 123855-51-6
tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate

: 193002-25-4
7-hydroxy-6-methoxy-3-pivaloyloxymethyl-3,4-dihydroquinazolin-4-one

: 264208-86-8
7-(1-(tert-butoxycarbonyl)piperidin-4-ylmethoxy)-6-methoxy-3-((pivaloyloxy)methyl)-3,4-dihydroxyquinazolin-4-one

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In dichloromethane; at 20 ℃; for 0.5h;
DOI:10.1021/jm011022e

Reference yield: 78.5%

: 193002-25-4
7-hydroxy-6-methoxy-3-pivaloyloxymethyl-3,4-dihydroquinazolin-4-one

: 166815-96-9
N-tert-butoxycarbonyl-4-(4-toluenesulphonyloxymethyl)piperidine

: 264208-86-8
7-(1-(tert-butoxycarbonyl)piperidin-4-ylmethoxy)-6-methoxy-3-((pivaloyloxy)methyl)-3,4-dihydroxyquinazolin-4-one

Guidance literature:: 7-hydroxy-6-methoxy-3-pivaloyloxymethyl-3,4-dihydroquinazolin-4-one; With potassium carbonate; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 0.5h;

N-tert-butoxycarbonyl-4-(4-toluenesulphonyloxymethyl)piperidine; In DMF (N,N-dimethyl-formamide); at 100 ℃; for 2h;