2-(3-Methyl-2-oxo-1,4-diphenyl-3-azetidinyl)-1H-isoindole-1,3(2H)-dione

Base Information

Chemical Name:2-(3-Methyl-2-oxo-1,4-diphenyl-3-azetidinyl)-1H-isoindole-1,3(2H)-dione
CAS No.:33745-24-3
Molecular Formula:C₂₄H₁₈N₂O₃
Molecular Weight:382.419
Hs Code.:
DSSTox Substance ID:DTXSID101152617

Synonyms:DTXSID101152617;2-(3-Methyl-2-oxo-1,4-diphenyl-3-azetidinyl)-1H-isoindole-1,3(2H)-dione;33745-24-3

Suppliers and Price of 2-(3-Methyl-2-oxo-1,4-diphenyl-3-azetidinyl)-1H-isoindole-1,3(2H)-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(3-Methyl-2-oxo-1,4-diphenyl-3-azetidinyl)-1H-isoindole-1,3(2H)-dione

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:382.13174244
Heavy Atom Count:29
Complexity:670

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(C(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3)N4C(=O)C5=CC=CC=C5C4=O

Technology Process of 2-(3-Methyl-2-oxo-1,4-diphenyl-3-azetidinyl)-1H-isoindole-1,3(2H)-dione

There total 6 articles about 2-(3-Methyl-2-oxo-1,4-diphenyl-3-azetidinyl)-1H-isoindole-1,3(2H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 538-51-2
benzylidene phenylamine

: 53701-47-6
2-(1,3-dioxoisoindolin-2-yl)propanoyl chloride

: 33745-24-3,85071-36-9,85071-38-1
(+/-)-(E)-1,4-diphenyl-3-methyl-3-phthaloylaminoazetidin-2-one

Guidance literature:: With triethylamine; In dichloromethane;

Reference yield: 20.0%

: 538-51-2
benzylidene phenylamine

: 53701-47-6
2-(1,3-dioxoisoindolin-2-yl)propanoyl chloride

: 33745-24-3,85071-36-9,85071-38-1
(+/-)-(E)-1,4-diphenyl-3-methyl-3-phthaloylaminoazetidin-2-one

: (+/-)-3,4-diphenyl-5-methyl-5-phthaloylamino-2-(1-phthaloylaminoethylidene)tetrahydro-1,3-oxazin-6-one

Guidance literature:: With triethylamine; In dichloromethane; Ambient temperature;

Reference yield:

: 21860-84-4
2-phthalimidopropionic acid

: 33745-24-3,85071-36-9,85071-38-1
(+/-)-(E)-1,4-diphenyl-3-methyl-3-phthaloylaminoazetidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / benzene / 2 h / Heating

2: Et₃N / benzene / Heating

With thionyl chloride; triethylamine; In benzene;