3-Nitro-4-(piperidin-1-yl)pyridine

Base Information

Chemical Name:3-Nitro-4-(piperidin-1-yl)pyridine
CAS No.:85868-36-6
Molecular Formula:C10H13N3O2
Molecular Weight:207.232
Hs Code.:2933990090
DSSTox Substance ID:DTXSID90393155
Wikidata:Q82191801
Mol file:85868-36-6.mol

Synonyms:3-Nitro-4-(piperidin-1-yl)pyridine;85868-36-6;3-nitro-4-piperidin-1-ylpyridine;3-nitro-4-piperidinopyridine;AC-907/25005067;SCHEMBL1710516;DTXSID90393155;ZITKFLGHHRRQNW-UHFFFAOYSA-N;CS-0359916;FT-0767065

Suppliers and Price of 3-Nitro-4-(piperidin-1-yl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
3-Nitro-4-(piperidin-1-yl)pyridine 95+%
1g
$ 518.00

Chemenu
3-nitro-4-(piperidin-1-yl)pyridine 95%
1g
$ 489.00

Alichem
3-Nitro-4-(piperidin-1-yl)pyridine
1g
$ 464.20

Total 7 raw suppliers

Chemical Property of 3-Nitro-4-(piperidin-1-yl)pyridine

Chemical Property:

Vapor Pressure:3.69E-05mmHg at 25°C
Boiling Point:353°C at 760 mmHg
Flash Point:167.3°C
PSA：61.95000
Density:1.242g/cm³
LogP:2.56830
Storage Temp.:2-8°C
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:207.100776666
Heavy Atom Count:15
Complexity:223

Purity/Quality:

95% ^*data from raw suppliers

3-Nitro-4-(piperidin-1-yl)pyridine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C2=C(C=NC=C2)[N+](=O)[O-]

Technology Process of 3-Nitro-4-(piperidin-1-yl)pyridine

There total 1 articles about 3-Nitro-4-(piperidin-1-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5435-54-1
4-hydroxy-3-nitropyridine

: 85868-36-6
3-nitro-4-(piperidin-1-yl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate / toluene / 110 °C

2: ethanol

With trichlorophosphate; In ethanol; toluene;
DOI:10.1039/c4tc01791a

Reference yield: 100.0%

: 85868-36-6
3-nitro-4-(piperidin-1-yl)pyridine

: 52311-36-1
4-(piperidin-1-yl)-3-aminopyridine

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; for 16h; under 760.051 Torr;

Reference yield:

: 85868-36-6
3-nitro-4-(piperidin-1-yl)pyridine

: 1346674-00-7
2-bromo-6-(1-oxo-3,4,6,7,8,9-hexahydropyrido[3,4-b]imidazo[4,5-c]pyridine-2-yl)benzyl acetate

Guidance literature:: Multi-step reaction with 5 steps

1.1: triethyl phosphite / 24 h / 110 °C / Inert atmosphere

2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 1.5 h / 0 - 20 °C

3.1: acetic anhydride / 1.5 h / 140 °C / Inert atmosphere

4.1: hydrogen; acetic acid / palladium 10% on activated carbon / 48 h / 85 °C / 18100.7 Torr

4.2: pH 9

5.1: caesium carbonate / copper(l) iodide / 1-methyl-pyrrolidin-2-one / 16 h / 120 °C / Inert atmosphere

5.2: 2 h / 20 °C

With hydrogen; acetic anhydride; caesium carbonate; acetic acid; 3-chloro-benzenecarboperoxoic acid; triethyl phosphite; copper(l) iodide; palladium 10% on activated carbon; In 1-methyl-pyrrolidin-2-one; dichloromethane;