4-Chloroquinolin-2-amine

Base Information

Chemical Name:4-Chloroquinolin-2-amine
CAS No.:20151-42-2
Molecular Formula:C9H7ClN2
Molecular Weight:178.621
Hs Code.:2933499090
European Community (EC) Number:872-766-1
ChEMBL ID:CHEMBL4461653
DSSTox Substance ID:DTXSID80555321
Nikkaji Number:J2.269.061B
Wikidata:Q82436634
Mol file:20151-42-2.mol

Synonyms:4-Chloroquinolin-2-amine;20151-42-2;2-AMINO-4-CHLOROQUINOLINE;CHEMBL4461653;4-chloro-quinolin-2-ylamine;4-chloroquinoline amine;4-chloro-quinolin2-ylamine;2-Quinolinamine, 4-chloro-;SCHEMBL1845197;DTXSID80555321;WHFKEBBQPCDRND-UHFFFAOYSA-N;BDBM50520372;AKOS006288571;AT23422;SB68161;CS-0136309;EN300-199408;4-Chloro-2-quinolinamine;2-Amino-4-chloroquinoline;Z1198181928

Suppliers and Price of 4-Chloroquinolin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-chloroquinolin-2-amine
10mg
$ 45.00

Crysdot
4-Chloroquinolin-2-amine 95+%
1g
$ 772.00

Chemenu
4-chloroquinolin-2-amine 95%
1g
$ 729.00

Biosynth Carbosynth
4-Chloroquinolin-2-amine
250 mg
$ 450.00

American Custom Chemicals Corporation
2-AMINO-4-CHLOROQUINOLINE 95.00%
5MG
$ 497.40

Alichem
4-Chloroquinolin-2-amine
1g
$ 850.20

AK Scientific
4-Chloroquinolin-2-amine
250mg
$ 481.00

Total 10 raw suppliers

Chemical Property of 4-Chloroquinolin-2-amine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:136 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
Boiling Point:327.331°C at 760 mmHg
PKA:5.20±0.50(Predicted)
Flash Point:151.764°C
PSA：38.91000
Density:1.363g/cm³
LogP:3.05160
Storage Temp.:2-8°C
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:178.0297759
Heavy Atom Count:12
Complexity:163

Purity/Quality:

NLT 98% ^*data from raw suppliers

4-chloroquinolin-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CC(=N2)N)Cl

Technology Process of 4-Chloroquinolin-2-amine

There total 7 articles about 4-Chloroquinolin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 703-61-7
2,4-dichloroquinoline

: 20151-42-2
4-chloro-quinolin-2-ylamine

Guidance literature:: 2,4-dichloroquinoline; With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; In toluene; at 20 ℃; for 0.0833333h; Inert atmosphere;

With Benzophenone imine; In toluene; at 100 ℃; for 3h;

With hydrogenchloride; In tetrahydrofuran;

Reference yield: 49.0%

: 4637-59-6
4-Chloroquinoline N-oxide

: 76-05-1
trifluoroacetic acid

: 20151-42-2
4-chloro-quinolin-2-ylamine

Guidance literature:: 4-Chloroquinoline N-oxide; With p-toluenesulfonylanhydride; tert-butylamine; In dichloromethane; at 0 - 20 ℃; for 0.5h;

trifluoroacetic acid; In dichloromethane; for 3h; Reflux;