(3S,7R)-3,7-dimethyldecyl tosylate

Base Information

• Chemical Name: (3S,7R)-3,7-dimethyldecyl tosylate
• CAS No.: 161795-03-5
• Molecular Formula: C₁₉H₃₂O₃S
• Molecular Weight: 340.527
• Mol file: 161795-03-5.mol

Synonyms:

Chemical Property of (3S,7R)-3,7-dimethyldecyl tosylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3S,7R)-3,7-dimethyldecyl tosylate

There total 14 articles about (3S,7R)-3,7-dimethyldecyl tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-3,7-dimethyl-6-octen-1-ol (7540-51-4) → (3S,7R)-3,7-dimethyldecyl tosylate (161795-03-5)

Guidance literature:

Multi-step reaction with 10 steps

1: 27.0 g / NaH / 1,2-dimethoxy-ethane

2: 89 percent / Ph₂Se₂, H₂O₂, t-BuOOH

3: 1.) O₃; 2.) NaBH₄ / 1.) CH₂Cl₂, CH₃OH

4: pyridine

5: NaI / acetone

6: 91 percent / dimethylformamide / 12 h / Ambient temperature

7: 1.) n-BuLi / 1.) hexane, THF, HMPA, -30 deg C, 1 h; 2.) hexane, THF, HMPA, r.t., 12 h

8: 81 percent / Na-Hg / ethanol / 40 h / Ambient temperature

9: 98 percent / H₂ / 10percent Pd/C / ethanol / 2 h / 760 Torr / Ambient temperature

10: pyridine / 12 h / 0 - 5 °C

With pyridine; tert.-butylhydroperoxide; sodium tetrahydroborate; n-butyllithium; sodium amalgam; diphenyl diselenide; hydrogen; dihydrogen peroxide; sodium hydride; ozone; sodium iodide; palladium on activated charcoal; In 1,2-dimethoxyethane; ethanol; N,N-dimethyl-formamide; acetone;

Reference yield:

(S)-((3,7-dimethyloct-6-enyloxy)methyl)benzene (84237-05-8) → (3S,7R)-3,7-dimethyldecyl tosylate (161795-03-5)

Guidance literature:

Multi-step reaction with 9 steps

1: 89 percent / Ph₂Se₂, H₂O₂, t-BuOOH

2: 1.) O₃; 2.) NaBH₄ / 1.) CH₂Cl₂, CH₃OH

3: pyridine

4: NaI / acetone

5: 91 percent / dimethylformamide / 12 h / Ambient temperature

6: 1.) n-BuLi / 1.) hexane, THF, HMPA, -30 deg C, 1 h; 2.) hexane, THF, HMPA, r.t., 12 h

7: 81 percent / Na-Hg / ethanol / 40 h / Ambient temperature

8: 98 percent / H₂ / 10percent Pd/C / ethanol / 2 h / 760 Torr / Ambient temperature

9: pyridine / 12 h / 0 - 5 °C

With pyridine; tert.-butylhydroperoxide; sodium tetrahydroborate; n-butyllithium; sodium amalgam; diphenyl diselenide; hydrogen; dihydrogen peroxide; ozone; sodium iodide; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide; acetone;

Reference yield:

(S,E)-8-(benzyloxy)-2,6-dimethyl-3-octen-2-ol (161905-08-4) → (3S,7R)-3,7-dimethyldecyl tosylate (161795-03-5)

Guidance literature:

Multi-step reaction with 8 steps

1: 1.) O₃; 2.) NaBH₄ / 1.) CH₂Cl₂, CH₃OH

2: pyridine

3: NaI / acetone

4: 91 percent / dimethylformamide / 12 h / Ambient temperature

5: 1.) n-BuLi / 1.) hexane, THF, HMPA, -30 deg C, 1 h; 2.) hexane, THF, HMPA, r.t., 12 h

6: 81 percent / Na-Hg / ethanol / 40 h / Ambient temperature

7: 98 percent / H₂ / 10percent Pd/C / ethanol / 2 h / 760 Torr / Ambient temperature

8: pyridine / 12 h / 0 - 5 °C

With pyridine; sodium tetrahydroborate; n-butyllithium; sodium amalgam; hydrogen; ozone; sodium iodide; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide; acetone;

upstream raw materials:

p-toluenesulfonyl chloride

(3S,7R)-3,7-dimethyl-1-decanol

(S)-3,7-dimethyl-6-octen-1-ol

(S)-((3,7-dimethyloct-6-enyloxy)methyl)benzene